The Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC) in Berlin, Germany is one of the sixteen research centers of the Helmholtz Association of German Research Centres.

Website
https://www.mdc-berlin.de/
Wikipedia
https://en.wikipedia.org/wiki/Max_Delbr%C3%BCck_Center_for_Molecular_Medicine_in_the_Helmholtz_Association

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Epigenetic mechanism appears to strongly influence healthy aging

Researchers at the Max Delbrueck Center for Molecular Medicine (MDC) have identified an epigenetic mechanism that appears to strongly influence healthy aging. It's a protein that controls muscle integrity, lifespan and levels ...

Keeping a cell's powerhouse in shape

A German-Swiss team around Professor Oliver Daumke from the MDC has investigated how a protein of the dynamin family deforms the inner mitochondrial membrane. The results, which also shed light on a hereditary disease of ...

Mole rats are pain-free, thanks to evolution

African mole rats are insensitive to many kinds of pain. As an international research team led by the MDC's Gary Lewin reports in Science, this characteristic has allowed mole rats to populate new habitats. Thanks to a genetic ...

On the origin of B1 cells

A new MDC study may resolve a decades-old debate in immunology. A team led by Professor Klaus Rajewsky reports in Science that distinct progenitor cells are not required for the development of B1 cells. Instead, the team's ...

A case of 'kiss and tell': Chromosomal kissing gets less elusive

How are chromosomes arranged in the cell nucleus? Is it possible that they communicate with one another by "touching" each other? To answer this question and to shed more light on the fundamental properties of the communication ...

A complete cell atlas and lineage tree of the immortal flatworm

From one stem cell to many differentiated body cells: Scientists from the MDC in Berlin, along with collaborating researchers in Munich, have published a comprehensive lineage tree of a whole adult animal in the journal Science. ...

How cells protect themselves against mechanical stress

The Piezo1 and Piezo2 ion channels are known to open up response to the slightest mechanical stimulus. MDC researchers have now discovered that the channels are also sensitive to changes in membrane voltage. The voltage sensitivity ...

Reproducing the computational environments of experiments

Experiments increasingly rely on high-performance computing software. Differences in software environments can cause problems when those experiments need to be reproduced—so scientists at the MDC in Berlin are seeking a ...

Reconstructing life at its beginning, cell by cell

After 13 rapid divisions a fertilized fly egg consists of about 6,000 cells. They all look alike under the microscope. However, each cell of a Drosophila melanogaster embryo already knows by then whether it is destined to ...

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