The Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC) in Berlin, Germany is one of the sixteen research centers of the Helmholtz Association of German Research Centres.

Website
https://www.mdc-berlin.de/
Wikipedia
https://en.wikipedia.org/wiki/Max_Delbr%C3%BCck_Center_for_Molecular_Medicine_in_the_Helmholtz_Association

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Mole rats are pain-free, thanks to evolution

African mole rats are insensitive to many kinds of pain. As an international research team led by the MDC's Gary Lewin reports in Science, this characteristic has allowed mole rats to populate new habitats. Thanks to a genetic ...

Keeping a cell's powerhouse in shape

A German-Swiss team around Professor Oliver Daumke from the MDC has investigated how a protein of the dynamin family deforms the inner mitochondrial membrane. The results, which also shed light on a hereditary disease of ...

On the origin of B1 cells

A new MDC study may resolve a decades-old debate in immunology. A team led by Professor Klaus Rajewsky reports in Science that distinct progenitor cells are not required for the development of B1 cells. Instead, the team's ...

A complete cell atlas and lineage tree of the immortal flatworm

From one stem cell to many differentiated body cells: Scientists from the MDC in Berlin, along with collaborating researchers in Munich, have published a comprehensive lineage tree of a whole adult animal in the journal Science. ...

Reconstructing life at its beginning, cell by cell

After 13 rapid divisions a fertilized fly egg consists of about 6,000 cells. They all look alike under the microscope. However, each cell of a Drosophila melanogaster embryo already knows by then whether it is destined to ...

Circular RNA linked to brain function

While hundreds of circular RNAs (circRNAs) are abundant in mammalian brains, one big question has remained unanswered: What are they actually good for? In the current issue of Science, Nikolaus Rajewsky and his team at the ...

How proteins reshape cell membranes

Small "bubbles" frequently form on membranes of cells and are taken up into their interior. The process involves EHD proteins - a focus of research by Prof. Oliver Daumke of the MDC. He and his team have now shed light on ...

Genome editing: Efficient CRISPR experiments in mouse cells

In order to use the CRISPR-Cas9 system to cut genes, researchers must design an RNA sequence that matches the DNA of the target gene. Most genes have hundreds of such sequences, with varying activity and uniqueness in the ...

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