Unexpected role of iASPP as a tumor suppressor
There is a tightly regulated balance between cell growth and death in healthy tissue. The loss of this balance is essentially what initiates cancer.
Ludwig Cancer Research is an international community of scientists focused on cancer research, with the goals of preventing and controlling cancer.[1] It encompasses the Ludwig Institute for Cancer Research, an international non-profit organization founded in 1971 by philanthropist Daniel K. Ludwig. The Institute is headquartered in New York City with a European office located in Zurich. In addition, six Ludwig Centers were established at leading US cancer research institutions. Together, the Institute and Centers are known as Ludwig Cancer Research.
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There is a tightly regulated balance between cell growth and death in healthy tissue. The loss of this balance is essentially what initiates cancer.
Cell & Microbiology
Oct 19, 2022
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Extracellular Signal Regulated Kinase (ERK) plays an important role in multiple cell signaling processes, by catalyzing the phosphorylation of a variety of substrates. The enzyme itself is activated by phosphorylation at ...
Molecular & Computational biology
Nov 14, 2022
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1
Single-cell transcriptomics is revolutionizing the field of cell biology. This technique enables researchers to analyze the genes expressed in individual cells, which provides more information on the different cell types ...
Cell & Microbiology
Aug 18, 2022
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8
Stem cells balance self-renewal with differentiation into mature cells. A fundamental and intriguing question is when during the process of maturation a cell reaches a "point of no return," losing its capacity to self-renew ...
Cell & Microbiology
Dec 1, 2021
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4
Factor Inhibiting Hypoxia Inducible Factor (FIH) has an important role in the response to low oxygen (hypoxia) in animals. FIH adds a hydroxyl (-OH) group onto the master regulator Hypoxia Inducible Factor (HIF), influencing ...
Biochemistry
May 24, 2022
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