This article has been reviewed according to Science X's editorial process and policies. Editors have highlighted the following attributes while ensuring the content's credibility:


peer-reviewed publication

trusted source


How fingerprints get their unique whorls

How fingerprints get their unique whorls
Graphical abstract. Credit: Cell (2023). DOI: 10.1016/j.cell.2023.01.015

An international team of scientists with a myriad of backgrounds has revealed the process by which unique fingerprints develop. In their research, published open access in the journal Cell, the group studied the development of fingerprints in mice and humans.

Prior study of fingerprints has shown that their purpose is to provide added grip and to enhance sensitivity. Scientists and lay people alike have known for a long time that in humans, they are unique—even identical twins have different prints. Why this is the case has remained a mystery. In this new effort, the researchers have solved the mystery.

To better understand how fingerprints develop and why they differ between people, the group tracked their formation in fetal mice and studied the genetics behind their development. They found what is known as a Turing reaction-diffusion system.

Back in the 1950s, Alan Turing proposed a development process by which leaves grow in unique arrangements. He suggested that some molecules in a developing system promote while others actively work to prevent growth. The result was two forces acting against one another on adjoining cells. That led to the creation of ridges, which led to unique formations, such as stripes on a zebra or whorls on fingertips.

By watching as fingerprints developed on fetal mice (and in a ), the researchers could see that ridges developed and worked against one another in three different parts of the end of the finger—the tip, the center, and the part closest to the top knuckle. As different cell groups pushed against one another relative to their , whorl patterns emerged.

The random placement of the fingers in the womb as the cells push against one another to form ridges is what makes the patterns so random. And that is why even identical twins have different prints. The team also found that the initial stages of fingerprint development were nearly identical to those of hair follicles. The only difference was that with hair follicles, cells deeper below the skin surface were involved in the process.

More information: James D. Glover et al, The developmental basis of fingerprint pattern formation and variation, Cell (2023). DOI: 10.1016/j.cell.2023.01.015

Journal information: Cell

© 2023 Science X Network

Citation: How fingerprints get their unique whorls (2023, February 10) retrieved 3 March 2024 from
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.

Explore further

Fingerprint patterns are linked to limb development genes


Feedback to editors