Uncommon byproducts of organochlorine pesticides found in the livers of raptors

A research team in Ehime University, Japan conducted a comprehensive profiling of chlorinated and brominated compounds bioaccumulated in the liver of various wild bird species from Osaka, Japan in order to find potentially harmful but "hidden" contaminants. The team found a specific accumulation of several groups of typically unmonitored halogenated contaminants in raptors, including those so far never been reported in wild animals. The findings were published in Environmental Science & Technology on June 8, 2021.

Ecological risk assessment of halogenated contaminants is an important issue, as many of these chemicals persist in the environment, bioaccumulate through the food web, and can cause lasting adverse effects. Chemicals listed as persistent organic pollutants (POPs) under the Stockholm Convention—including legacy industrial chemicals such as polychlorinated biphenyls (PCBs) and legacy organochlorine pesticides such as dichlorodiphenyltrichloroethane (DDT) and chlordane, etc.—are monitored in the environment, animals, and humans by national and international programs, typically using chemical analysis targeting specific predetermined groups of POPs. However, conventional analytical methods cannot detect untargeted contaminants such as chemical synthesis byproducts, and environmental transformation products. There is increasing evidence for the occurrence of many typically unmonitored and unknown bioaccumulative contaminants in the environment and biota, but the accumulation levels and behavior of such POPs-like contaminants in various food webs remain unclear.

The research team in Ehime University used advanced analytical methods based on two-dimensional gas chromatography (GC×GC), time-of-flight mass spectrometry (ToFMS), and software mass spectral filtering for comprehensive profiling of chlorinated and brominated contaminants in the liver of terrestrial and brackish water bird species from Osaka, Japan. Relatively high levels of typically unmonitored halogenated contaminants, including polychlorinated terphenyls (PCTs), various DDT- and chlordane-related compounds, were found in raptors. Notably, chlordane byproducts with C₁₅-based structures were detected for the first time in wild animals and showed high biomagnification potential in the terrestrial food web. These findings highlight the need for further studies on occurrence, structure elucidation and toxicological assessment of unmonitored POPs-like contaminants.