Researchers develop diagnostic tool for detecting cryptosporidium

UBC researchers develop diagnostic tool for detecting cryptosporidium
Engineering doctoral student George Luka says there is an urgent need to develop a fast, flexible, accurate and real-time detection tool to meet the challenge of protecting water consumers. Credit: UBC Okanagan

A handheld 'tricorder' that can test for biological contamination in real-time has been the dream of science fiction fans for decades. And UBC Okanagan engineers say the technology is closer to science fact than ever before.

Using a small and inexpensive biosensor, researchers in the School of Engineering have developed a novel low-cost technique that quickly and accurately detects contamination in .

Cryptosporidium is an intestinal pathogen and one of the leading causes of respiratory and gastrointestinal illness in the world. Drinking water contaminated with the parasite can result in diarrhea and, in extreme cases, can even lead to death.

"Current methods for detecting cryptosporidium require filtering large volumes of water, separating out the organisms, staining them with a fluorescence label and trying to identify the pathogen using a microscope," says George Luka, a at UBC Okanagan's School of Engineering and study lead author. "The process is extremely slow, expensive and doesn't yield reliable results."

Luka says there is an urgent need to develop a fast, flexible, accurate and real-time detection tool to meet the challenge of protecting water consumers from this common and potentially dangerous contaminent.

To solve this problem, Luka and his colleagues tested a specially designed and calibrated biosensor. Using varying concentrations of pathogen in water samples, they were able establish its ability to detect cryptosporidium contamination.

"The biosensor performed exactly as we were hoping and was able to measure cryptosporidium contamination rapidly and without the need for complex preparations and highly-trained technicians," says Luka. "This is an impressive solution that can easily be integrated into inexpensive and to test drinking water in real-time anywhere in the world."

Luka also says the biosensor can be expanded to measure other biomarkers and hazards.

"The technology has real potential to be used to test all kinds of biological contamination, both in medical and environmental applications. A handheld sensor that tests the safety of our and our environment could soon become a reality."

The research was published recently in the journal Sensors.


Explore further

Where does this contamination come from?

More information: George Luka et al, Label-Free Capacitive Biosensor for Detection of Cryptosporidium, Sensors (2019). DOI: 10.3390/s19020258
Citation: Researchers develop diagnostic tool for detecting cryptosporidium (2019, February 14) retrieved 20 May 2019 from https://phys.org/news/2019-02-diagnostic-tool-cryptosporidium.html
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.
4 shares

Feedback to editors

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more