Researchers provide update on popular fish model of development

Researchers provide update on popular fish model of development
Credit: Wiley

Annual killifish are an excellent animal model for research on interactions between genes and the environment during development. A new article describes the development of one particular South American species of this fish in great detail and updates the classic embryo staging guide developed in 1972.

The methodological guide will be very useful for scientists who study killifish and will also likely encourage other to consider this fascinating vertebrate model system.

"Annual killifish are amazing creatures. They have evolved to survive in temporary ponds miles from permanent water by producing embryos that arrest development in up to three stages of diapause. While the adult fish die when the ponds dry, the embryos can survive for months without water, and without oxygen," said Dr. Jason Podrabsky, lead author of the Developmental Dynamics article. When faced with lack of oxygen, the heart of the embryo stops beating and the embryo's is severely reduced, he explained.

"These offer the opportunity to study the limits of vertebrate survival of extreme conditions and how the environment may alter , and they may help us to understand how to mitigate damage due to heart attack and stroke in humans."

More information: Jason E. Podrabsky et al. Embryonic development of the annual killifish: An emerging model for ecological and evolutionary developmental biology research and instruction, Developmental Dynamics (2017). DOI: 10.1002/dvdy.24513

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Citation: Researchers provide update on popular fish model of development (2017, May 9) retrieved 24 June 2024 from
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