New genetic evidence resolves origins of modern Japanese

March 11, 2015

Was there a single migration event or gradual mixing of cultures that gave rise to modern Japanese?

According to current theory, about 2,000-3,000 years ago, two populations, the hunter-gatherer Jomon from the Japanese archipelago, and the agricultural Yayoi from continental East Asia, intermingled to give rise to the modern Japanese population. However, some researchers have suggested otherwise, with the Jomon culture gradually transformed into the Yayoi culture without large migrations into modern day Japan.

To resolve the controversy, researchers Oota, Mano, Nakagome et al., identified the differences between the Ainu people (direct descendants of indigenous Jomon) with Chinese from Beijing (same ancestry as Yayoi).

The results from a genome-wide, (SNP) data strongly support the hybridization model as the best fit for Japanese population history. An initial divergence between the Ainu and Beijing group was dated to approximately 20,000 years ago, while evidence of genetic mixing occurred 5,000 to 7,000 years ago, older than estimates from the archaeological records, probably due to the effect of a further sub-population structure of the Jomon people.

The authors caution that further studies will need to be undertaken (especially ancient genome analysis of Jomon and Yayoi skeletal remains and genomic analysis of northeast Asians) to untangle the true evolutionary history of Japanese, in particular, the origins of the Jomon and Yayoi people and the source of gene flow to the Ainu.

The study is published in Molecular Biology and Evolution.

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JVK
1 / 5 (4) Mar 11, 2015
In 2014, others reported what appears to be an RNA-mediated UV light-induced amino acid substitution that may be linked from nutrient uptake to RNA-directed DNA methylation and ecological adaptation in a modern human population.

Nutrient-dependent pheromone-controlled fixation of the replacement of leucine with isoleucine at the 418th amino acid of HYAL2 and suppression of the oncogenic virus Jaagsiekte sheep retrovirus appears to link the viral microRNA / nutrient-dependent microRNA balance and the survival of a modern human population via the physiology of their pheromone-controlled reproduction.

Sunlight adaptation region of Neanderthal genome found in up to 65 percent of modern East Asian population
http://phys.org/n...tml#nRlv

The similarities in the mouse-to-human model of the link from EDAR to cell type differentiation are more likely to link top-down causation that mutations to biodiversity
Vietvet
4.3 / 5 (6) Mar 11, 2015
Jvk has no shame in promoting in his pseudo science creationist beliefs.
JVK
1 / 5 (4) Mar 11, 2015
Nutrient-dependent/pheromone-controlled adaptive evolution: a model
http://www.ncbi.n...3960065/

Excerpt: Two additional recent reports link substitution of the amino acid alanine for the amino acid valine (Grossman et al., 2013) to nutrient-dependent pheromone-controlled adaptive evolution. The alanine substitution for valine does not appear to be under any selection pressure in mice. The cause-and-effect relationship was established in mice by comparing the effects of the alanine, which is under selection pressure in humans, via its substitution for valine in mice (Kamberov et al., 2013).

These two reports (Grossman et al., 2013; Kamberov et al., 2013) tell a new short story of adaptive evolution. The story begins with what was probably a nutrient-dependent variant allele that arose in central China approximately 30,000 years ago."

The story is about ecological variation and ecological adaptation that, as usual is told as one about evolution.
JVK
1 / 5 (4) Mar 12, 2015
See also: These reports address the most recent work that links RNA-directed DNA methylation to RNA-mediated amino acid substitutions and cell type differentiation, which links the physiology of reproduction to the morphological and behavioral phenotypes of species from microbes to man.

RNA directed DNA methylation and cell types
http://rna-mediat...l-types/

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