A team of researchers has developed an innovative method to design complicated all-α proteins, characterized by their non-uniformly arranged α-helices as seen in hemoglobin. Employing their novel approach, the team successfully ...
Molecular & Computational biology
Jan 4, 2024
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61
In a complex called chromatin, long strands of DNA in cells' nuclei are tightly wrapped around a scaffolding of proteins, like a rolled-up ball of yarn. A new study by Weill Cornell Medicine investigators reveals that beyond ...
Cell & Microbiology
Jan 2, 2024
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70
A research group led by Professor Nobuo Noda of Hokkaido University has reconstituted the membrane invagination process required to form autophagosomes in vitro for the first time, showing that this process is mediated by ...
Molecular & Computational biology
Dec 20, 2023
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2
Cell biologists from RIKEN have provided an unprecedented glimpse into the distinctive features of an unusual chromosome—the inactivated X chromosome copy carried by every female cell. The findings are published in the ...
Cell & Microbiology
Nov 14, 2023
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54
Depression, obesity or chronic pain—all of these disorders can be triggered or promoted by stress. In two publications, researchers at TU Darmstadt show new ways of treating stress-related diseases.
Biochemistry
Nov 10, 2023
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53
Scientists have breathed new life into the study of a protein with an outsized link to human cancers because of its dangerous mutations, using advanced research techniques to detect its hidden regions.
Cell & Microbiology
Oct 18, 2023
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31
Researchers at Weill Cornell Medicine have illuminated one of the important ways that cells respond to stress. The findings could also be relevant to Alzheimer's, ALS and other diseases in which this mechanism may be abnormally ...
Cell & Microbiology
Sep 28, 2023
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2
Actin filaments are dynamic protein-fibers in the cell built from single actin proteins. Many cellular functions, including cell movement, are regulated by constant filament assembly and disassembly. The disassembly phase ...
Cell & Microbiology
Sep 28, 2023
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33
Within the intricate molecular landscape inside of a cell, the orchestration of proteins demands precise control to avoid disease. While some proteins must be synthesized at specific times, others require timely breakdown ...
Cell & Microbiology
Sep 21, 2023
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32
Researchers at the Icahn School of Medicine at Mount Sinai have identified the structure of a special transporter found in red blood cells and how it interacts with drugs. Details on the findings, which were reported in the ...
Molecular & Computational biology
Sep 7, 2023
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