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Molecular & Computational biology news
Metagenomic profiling method with enhanced precision uses fewer computing resources
Researchers at Carnegie Mellon University and the University of Toronto have developed a new k-mer sketching metagenomic profiler, called sylph, that allows scientists to analyze genomic data more quickly and precisely than ...
Biotechnology
2 hours ago
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A new vertical seed distribution trait for soybean breeding
As the human population increases and protein demand doubles, modern plant breeders must further optimize soybean plant architecture and per plant yield for modern farming systems.
Molecular & Computational biology
2 hours ago
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Barley pangenome study reveals diversity can arise after domestication
Pangenomes are collections of annotated genome sequences of multiple individuals of a species. The structural variants uncovered by these datasets are a major asset to genetic analysis in crop plants.
Molecular & Computational biology
3 hours ago
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Linking data on genetics, traits and environment gives crop breeders a wider lens
Understanding how both environmental conditions and genetic makeup affect crops is essential to developing varieties that are more resilient and productive. But the intricate interplay between weather and genes is difficult ...
Molecular & Computational biology
5 hours ago
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Drosophila study uncovers molecular details of how cell death is controlled during epithelial tissue remodeling
When complex multicellular organisms grow and develop, their tissues must undergo remodeling. As new cells begin to proliferate, old cells must be removed to make room and maintain tissue balance and function. One example ...
Cell & Microbiology
6 hours ago
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New daisy species discovered with refined DNA technology
Sometimes plants are so similar to each other that the methods developed by 18th-century scientist Carl Linnaeus for identifying species are not enough. In a thesis from the University of Gothenburg, completely new species ...
Plants & Animals
8 hours ago
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MassiveFold: Customizable version of AlphaFold reduces protein structure prediction time from months to hours
Scientists from Université de Lille, France, Linköping University, Sweden, and collaborating institutions have introduced MassiveFold, a new version of AlphaFold that dramatically reduces computing time for protein structure ...
Q&A: Making in situ serial crystallography more accessible
Scientists at EMBL Grenoble and the European Synchrotron Radiation Facility (ESRF) have developed a new method for using in situ serial crystallography (iSX) to study the structure of macromolecules. They recently described ...
Molecular & Computational biology
Nov 12, 2024
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Sweet switch: Sorbitol's key role in apple plant growth strategy
Apple trees, like many perennial plants, endure a prolonged juvenile stage before reaching maturity, during which they experience complex developmental changes. These transitions impact photosynthetic traits, growth rates, ...
Molecular & Computational biology
Nov 12, 2024
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Virtual fruity fly model can simulate sensory navigation
All animals, large or small, have to move at an incredible precision to interact with the world. Understanding how the brain controls movement is a fundamental question in neuroscience. For larger animals, this is challenging ...
Plants & Animals
Nov 12, 2024
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Self-organization of living matter into complex structures: How light pattern impacts aggregation of active filaments
When active filaments are exposed to localized illumination, they accumulate into stable structures along the boundaries of the illuminated area. Based on this fact, researchers at the Max Planck Institute for Dynamics and ...
Biotechnology
Nov 12, 2024
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Solving the bottleneck of conifer propagation: A molecular approach
Conifers are foundational to ecosystems globally, providing critical environmental and economic value. Yet, their long life cycles slow traditional breeding methods, positioning somatic embryogenesis (SE) as a more effective ...
Plants & Animals
Nov 12, 2024
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Scientists reveal structural basis for precursor protein import into chloroplasts
The TOC (Translocon at the Outer envelope of Chloroplasts)-TIC (Translocon at the Inner envelope of Chloroplasts) supercomplex is responsible for mediating the transport of most precursor proteins from the cytoplasm into ...
Cell & Microbiology
Nov 12, 2024
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Computer simulations reveal how cells break down the endoplasmic reticulum
Inside cells, there exists an extensive system of canals known as the endoplasmic reticulum (ER), which consists of membrane-encased tubes that are partially broken down as needed—for instance in case of a nutrient deficiency. ...
Cell & Microbiology
Nov 12, 2024
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Natural tolerance to weed killer uncovered in bryophytes
Herbicide resistance poses a challenge to producing enough food for a growing population. Sam Caygill and colleagues at the Gregor Mendel Institute (GMI) of the Austrian Academy of Sciences discovered how a large group of ...
Molecular & Computational biology
Nov 12, 2024
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DNA packaging directly affects how fast DNA is copied in cells, scientists discover
Researchers from the Mattiroli group have found that the way DNA is packaged in cells can directly impact how fast DNA itself is copied during cell division. They discovered that DNA packaging sends signals through an unusual ...
Cell & Microbiology
Nov 12, 2024
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Using CRISPR to decipher whether gene variants lead to cancer
In recent years, scientists have created a range of new methods based on CRISPR-Cas technology for precisely editing the genetic material of living organisms. One application is in cell therapy: A patient's immune cells can ...
Biotechnology
Nov 12, 2024
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New AI model improves prediction power for genomics related to disease
To understand the workings of DNA in relation to disease, scientists at Los Alamos National Laboratory have developed the first multimodal deep learning model of its kind, EPBDxDNABERT-2, capable of ascertaining the precise ...
Biotechnology
Nov 11, 2024
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3D leaf edge reconstruction method enhances plant morphology analysis
Leaves, essential for photosynthesis and other physiological functions, exhibit diverse shapes that help plants adapt to their environments. Traditional methods for measuring leaf morphology have relied heavily on 2D imaging, ...
Plants & Animals
Nov 11, 2024
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New CRISPR system for gene silencing doesn't rely on cutting DNA
Scientists from Vilnius University's (VU) Life Sciences Center (LSC) have discovered a unique way for cells to silence specific genes without cutting DNA. This research, led by Prof. Patrick Pausch and published in the journal ...
Biotechnology
Nov 11, 2024
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