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Screen reveals new proteins that control RNA processing

Researchers at the University of California San Diego have developed a large-scale screening approach that identifies proteins controlling a fundamental step in gene expression known as alternative polyadenylation (APA). ...

Secrets of how we see color revealed at the molecular level

A global team has cracked a decades-old mystery, revealing the atomic structures of the molecules in our eyes that allow us to see colors. "To understand how we detect light and perceive colors, we need to know the exact ...

Ultra-precise technology can count damaged DNA fragments

The Korea Research Institute of Standards and Science has developed an ultrasensitive immunoassay-based analytical platform that can detect and quantify trace amounts of "Small Excised Damaged DNA (sedDNA)" fragments generated ...

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Biotechnology
By making key signaling molecules called β-arrestins into druggable targets, scientists crack long-standing challenge
Biotechnology
CleanFinder brings browser-based genome editing analysis to labs without coding
Cell & Microbiology
How mitochondria build their protein factories could help explain energy‑linked disease
Molecular & Computational biology
Piecing the puzzle of how proteins fit together: Simpler model outperforms leading methods
Cell & Microbiology
Completing DNA replication triggers genomic instability in bacteria
Cell & Microbiology
Chloroplast study reveals molecular lock that helps power life on Earth
Cell & Microbiology
Discovery of how cells maintain their DNA could shield key healthy cells from chemotherapy side effects
Molecular & Computational biology
Four-decade mystery solved as PKCβ structure reveals new drug target
Plants & Animals
Plant protein pair reveals new wood-formation mechanism
Cell & Microbiology
DNA loops reveal how immune cells build millions of antibodies from one genome
Ecology
Honeybee metamorphosis map uncovers 842 active DNA switches that drive worker bee development
Evolution
Zebrafish and fruit flies share the same internal compass mechanism in a case of convergent evolution
Cell & Microbiology
Real-time imaging reveals 'RNA hub' driving adaptive immune response
Evolution
How thousands of nature's longest sperm squeeze into a tiny fruit fly
Molecular & Computational biology
Cats age like humans—could studying their brains reveal healthy aging secrets?
Ecology
Mosquito-borne viruses avoid killing hosts by limiting protein output, study reveals
Biotechnology
Protein-tagging technology maps a hidden communication network between organs
Biotechnology
CRISPR safety check evaluates intended and unintended mutations
Cell & Microbiology
Ordinary enzyme that evolves into 'control switch' reveals tuberculosis weak spot
Cell & Microbiology
Cryo-EM imaging reveals how a molecular gate lets bulky proteins pass cell membranes intact

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Archaeology
A goat's tooth may have solved a 100‑year debate about ancient Greek farming
Plants & Animals
There may be 3 times more insect species than previously thought
Earth Sciences
Ozone depletion began decades before discovery of ozone hole, scientists find
Archaeology
Bronze Age boat carvings point to maritime links from Iberia to Scandinavia
Plants & Animals
Spiders benefit from seemingly monotonous forests
Astronomy
Solar storms leave their mark on cosmic rays that reach Earth
Astronomy
Nova V612 Scuti's light curve becomes audio, revealing how stellar shocks evolved
Biochemistry
Light-activated compound kills antibiotic-resistant bacteria by turning its own defense enzyme against it
Analytical Chemistry
Switching spin states in manganese ions with light opens new path for molecular memory
Plants & Animals
Giraffes combine quantities similarly to addition
Planetary Sciences
Giant exoplanet may hold a magnetic grip on its host star
Earth Sciences
Uncovering the trigger behind slow earthquakes
Bio & Medicine
Why nanoscale droplets don't coalesce and microscale droplets do
Paleontology & Fossils
First ever dinosaur found in Antarctica described for science
Archaeology
Mummified dogs reveal Tiwanaku people buried companions beside homes long before they became status symbols
Social Sciences
Why people worldwide see some mental abilities as inborn and others as learned
Environment
Decline in plankton across Northeast Atlantic sends stark warning for ocean health
Ecology
Tiny DNA 'hitchhikers' may be reshaping life in thawing Arctic soils
Plants & Animals
Childbirth is not uniquely difficult to humans
Astronomy
Ultra-faint galaxy discovered near Andromeda may be 12.5 billion years old

A roadmap for safer, explainable protein-design AI

Protein language models are artificial intelligence tools which help engineer proteins with useful properties, including completely new structures never seen before in nature.

This anti-CRISPR stops the protein assembly line in bacteria

Bacteria fend off invading viruses with molecular scissors that slice up viral DNA—a system called CRISPR that's become indispensable to gene editing. But viruses can fight back with a molecular trick that stops the scissors ...