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Screen reveals new proteins that control RNA processing

Researchers at the University of California San Diego have developed a large-scale screening approach that identifies proteins controlling a fundamental step in gene expression known as alternative polyadenylation (APA). ...

Secrets of how we see color revealed at the molecular level

A global team has cracked a decades-old mystery, revealing the atomic structures of the molecules in our eyes that allow us to see colors. "To understand how we detect light and perceive colors, we need to know the exact ...

Ultra-precise technology can count damaged DNA fragments

The Korea Research Institute of Standards and Science has developed an ultrasensitive immunoassay-based analytical platform that can detect and quantify trace amounts of "Small Excised Damaged DNA (sedDNA)" fragments generated ...

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Cell & Microbiology
Completing DNA replication triggers genomic instability in bacteria
Cell & Microbiology
Chloroplast study reveals molecular lock that helps power life on Earth
Ecology
Honeybee metamorphosis map uncovers 842 active DNA switches that drive worker bee development
Molecular & Computational biology
Four-decade mystery solved as PKCβ structure reveals new drug target
Cell & Microbiology
Discovery of how cells maintain their DNA could shield key healthy cells from chemotherapy side effects
Plants & Animals
Plant protein pair reveals new wood-formation mechanism
Cell & Microbiology
DNA loops reveal how immune cells build millions of antibodies from one genome
Evolution
Zebrafish and fruit flies share the same internal compass mechanism in a case of convergent evolution
Cell & Microbiology
Real-time imaging reveals 'RNA hub' driving adaptive immune response
Evolution
How thousands of nature's longest sperm squeeze into a tiny fruit fly
Molecular & Computational biology
Cats age like humans—could studying their brains reveal healthy aging secrets?
Ecology
Mosquito-borne viruses avoid killing hosts by limiting protein output, study reveals
Cell & Microbiology
Cryo-EM imaging reveals how a molecular gate lets bulky proteins pass cell membranes intact
Biotechnology
Protein-tagging technology maps a hidden communication network between organs
Biotechnology
CRISPR safety check evaluates intended and unintended mutations
Cell & Microbiology
Ordinary enzyme that evolves into 'control switch' reveals tuberculosis weak spot
Ecology
Researchers reveal Hong Kong as a 'biodiversity ark' for yellow-crested cockatoos and expand nesting support
Molecular & Computational biology
Mapping cotton bacterial blight resistance
Molecular & Computational biology
Researchers develop antiviral candidate for deadly mosquito-borne brain infections
Cell & Microbiology
MINDY3: A hub between protein quality control and DNA repair

Other news

Nanophysics
Nanopattern method unlocks precise control of disorder for wave-guiding devices
Astronomy
Reanalysis suggests 'Phoebe' is a variable star, not a primordial black hole
Biochemistry
Injectable silk-kudzu hydrogel achieves complete wound closure in laboratory tests
Bio & Medicine
Shining blue light on gold-graphene nanodots achieves wound healing trifecta
Astronomy
Off-center stellar death points to wandering supermassive black hole stripped of its own galaxy
Space Exploration
NASA races to save Swift telescope from falling back to Earth with daring rescue mission
Earth Sciences
The sun's outbursts may briefly weaken rain and snow events across North America
General Physics
World's largest particle smasher halts for upgrade to boost hunt for dark matter
Evolution
Primate evolution kept aging rates stable for 25 million years despite lifespan gaps
Plants & Animals
The bond between humans and dogs remains remarkably consistent across societies, cross-cultural study reveals
Astronomy
New millisecond pulsar discovered with the Murchison Widefield Array
Earth Sciences
Coastal and estuarine carbon removal technique may backfire when pushed too far
Cell & Microbiology
Peptide alternative to antibiotics could combat antimicrobial resistance crisis
General Physics
Non-Hermitian geometry reveals when quantum amplification depends only on start and end points
Evolution
Newly identified fossil sheds light on evolutionary history of saber-toothed cats
Environment
Burned-home soils showed uneven lead, arsenic contamination after Los Angeles wildfires
Evolution
Lamprey brain atlas reveals 450-million-year blueprint of vertebrate brains
Other
Saturday Citations: Predicting earthquakes; two types of water; observing event horizons
Plants & Animals
Two humpback whales set records swimming between Australia and Brazil
Biochemistry
New workflow transforms nonfunctional protein scaffolds into active enzymes

Greenland shark genome reveals clues to 400-year lifespan

The first comprehensive map of nearly the entire Greenland shark genome is beginning to reveal some of the genetic clues behind its incredibly long life. The work could one day help scientists develop new cures and treatments ...

Cells have a built-in 'seatbelt' against sudden stress

When cells experience sudden physical stress, like stretching or pressure, they can activate a fast, protective mechanism that shields their nuclei from destruction, according to a new study published in the Biophysical Journal. ...

Genetically modified hookworms produce and deliver therapeutics

Hookworms, intestinal parasites that infect hundreds of millions of people in under-resourced tropical regions around the globe, have evolved to survive inside the human gut for years, secreting molecules that enable coexistence ...

Proteins can be selectively controlled with radio waves

In a significant advance in biological quantum sensing, a research team led by the Technical University of Munich (TUM) has discovered and tested a new mechanism of action in which proteins can be controlled with radio waves. ...

First human SMUG1 atomic snapshots reveal how cells repair DNA

Researchers have captured the first atomic structures of human SMUG1, an enzyme that helps cells repair damaged DNA. The findings provide new insight into how cells recognize and remove harmful DNA bases, and may support ...

'Genetic brakes' reveal how embryos shape their limbs

Canadian scientists have made a significant advance in understanding the mechanisms that enable embryos to properly form their limbs, thanks to new research led by Université de Montréal medical professor Marie Kmita at the ...