A 'stemness checkpoint' helps control stem cell identity

A study published in Cell Research advances a central idea in stem cell biology by identifying a checkpoint that controls the identity of many different types of stem cells across developmental stages. For nearly two decades, ...

Glucose transport may hinge on a fleeting transition-like state

Stockholm University and SciLifeLab researchers have uncovered how glucose transporters move nutrients into cells, bridging a long-standing gap between structure and function in membrane biology. "Our study shows that these ...

Split shift: A surprising twist in the biology of aging

A new Yale study of flatworms, a species with the unique ability to regenerate, reveals that disruptions in the body's internal map of cellular organization may play a part in age-related decline.

Researchers clarify how cells remove damaged endoplasmic reticulum

The cell's endoplasmic reticulum (ER) plays a central role in protein synthesis, folding, and calcium (Ca²⁺) storage. When damaged, ER-phagy (self-eating) removes affected ER regions via double-membrane vesicles called autophagosomes. ...

Cell 'snowball' may be answer to large-scale tissue engineering

Cell cultures—single layers of cells grown in a small dish—have enabled researchers to study biological growth, develop or test drugs and even discover what causes some diseases. Cell spheroids, 3D versions of cell cultures ...

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