Harvard University researchers at the Broad Institute report that expansion in situ genome sequencing (ExIGS) linked nuclear abnormalities to hotspots of aberrant chromatin regulation, potentially eroding cell identity. The ...
University of Pennsylvania researchers have discovered a right-handed, antiparallel double-helix inside influenza ribonucleoprotein complexes that slides strand-against-strand as the viral polymerase copies RNA, offering ...
An international team of scientists have unlocked a key piece of Earth's evolutionary puzzle by decoding the structure of a light-harvesting "nanodevice" in one of the planet's most ancient lineages of cyanobacteria.
Evolution
May 16, 2025
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115
Researchers from the Institute for Molecular Science (IMS)/SOKENDAI and Kyushu University have uncovered the molecular mechanism that drives the "ticking" of the circadian clock in cyanobacteria.
Cell & Microbiology
Jun 13, 2025
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Tuberculosis is the world's leading infectious cause of death, killing more than one million people each year. When the antibiotic bedaquiline was introduced in 2012, it was the first new tuberculosis drug in over 40 years. ...
Cell & Microbiology
Jun 13, 2025
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22
In a study published in Cell Research, a research team has, for the first time, resolved the high-resolution in situ structure of the central apparatus (CA) within the axoneme of mammalian sperm.
Cell & Microbiology
Jun 13, 2025
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39
Not all DNA looks like the familiar twisted ladder. Sometimes, parts of our genetic code fold into unusual shapes. One such structure, the G-quadruplex (G4), looks like a knot. These knots can play important roles in turning ...
Cell & Microbiology
Jun 12, 2025
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0
Scientists have discovered a gruesome microbial survival strategy: when food is scarce, some bacteria kill and consume their neighbors.
Ecology
Jun 12, 2025
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Genetic changes can occur naturally through evolution or can be initiated with the help of genetic engineering. The bacterium Thermoanaerobacter kivui (T. kivui) was manipulated by a research team led by Stefan Pflügl from ...
Cell & Microbiology
Jun 12, 2025
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Programmed cell death serves as a critical defense mechanism during viral infection. The kinases RIPK1 and RIPK3, central regulators of programmed cell death pathways, undergo precise modulation through various post-translational ...
Cell & Microbiology
Jun 12, 2025
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