A 'stemness checkpoint' helps control stem cell identity

A study published in Cell Research advances a central idea in stem cell biology by identifying a checkpoint that controls the identity of many different types of stem cells across developmental stages. For nearly two decades, ...

Glucose transport may hinge on a fleeting transition-like state

Stockholm University and SciLifeLab researchers have uncovered how glucose transporters move nutrients into cells, bridging a long-standing gap between structure and function in membrane biology. "Our study shows that these ...

AI uncovers hidden immune defenses inside bacteria

Researchers at the Massachusetts Institute of Technology (MIT) have discovered thousands of new proteins that protect bacteria from virus attacks using an AI system called DefensePredictor. What would usually take months ...

Split shift: A surprising twist in the biology of aging

A new Yale study of flatworms, a species with the unique ability to regenerate, reveals that disruptions in the body's internal map of cellular organization may play a part in age-related decline.

Researchers clarify how cells remove damaged endoplasmic reticulum

The cell's endoplasmic reticulum (ER) plays a central role in protein synthesis, folding, and calcium (Ca²⁺) storage. When damaged, ER-phagy (self-eating) removes affected ER regions via double-membrane vesicles called autophagosomes. ...

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