CRISPR editing of mitochondria: Promising new biotech?

Although the CRISPR/Cas9 system has seen widespread application in editing the nuclear genome, using it to edit the mitochondrial genome has been problematic. The main hurdles have been a lack of suitable editing sites in ...

A high-resolution glimpse of gene expression in cells

Using a novel technique for expanding tissue, MIT and Harvard Medical School researchers have devised a way to label individual molecules of messenger RNA within a tissue sample and then sequence the RNA.

In situ sequencing of the fully structured genome

There is a sense in which the information encoded in a gene sequence can be represented by two bits per base pair location. The reality, however, is that this is far from a complete description. Although many academically ...

Could COVID-19 have wiped out the Neandertals?

Everybody loves Neandertals, those big-brained brutes we supposedly outcompeted and ultimately replaced using our sharp tongues and quick, delicate minds. But did we really, though? Is it mathematically possible that we could ...

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