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New method to detect off-target effects of CRISPR

Since the CRISPR genome editing technology was invented in 2012, it has shown great promise to treat a number of intractable diseases. However, scientists have struggled to identify potential off-target effects in therapeutically ...

BRB-seq: The quick and cheaper future of RNA sequencing

RNA sequencing is a technique used to analyze entire genomes by looking at the expression of their genes. Today, such genome-wide expression analyses are a standard tool for genomic studies because they rely on high-throughput ...

CRISPR base editors can induce wide-ranging off-target RNA edits

A Massachusetts General Hospital (MGH) research team reports that several of the recently developed CRISPR base editors, which create targeted changes in a single DNA base, can induce widespread off-target effects in RNA, ...

A biosynthetic dual-core cell computer

ETH researchers have integrated two CRISPR-Cas9-based core processors into human cells. This represents a huge step towards creating powerful biocomputers.

Pollen genes mutate naturally in only some strains of corn

Pollen genes mutate naturally in only some strains of corn, according to Rutgers-led research that helps explain the genetic instability in certain strains and may lead to better breeding of corn and other crops.

Engineering 'hairpins' increases CRISPR accuracy

Biomedical engineers at Duke University have developed a method for improving the accuracy of the CRISPR genome editing technology by an average of 50-fold. They believe it can be easily translated to any of the editing technology's ...

To protect stem cells, plants have diverse genetic backup plans

Despite evolution driving a wide variety of differences, many plants function the same way. Now a new study has revealed the different genetic strategies various flowering plant species use to achieve the same status quo.

Genetic variant linked to cucumber fruit length

The cucumber is among the top five vegetable crops grown in the world. Cucumbers are most commonly eaten fresh or preserved as pickles. An important attribute of the cucumber is fruit length. Cucumbers range in size from ...

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Cell & Microbiology
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Biotechnology
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Biotechnology
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Biotechnology
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Biotechnology
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Biotechnology
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Biotechnology
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Biotechnology
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Biotechnology
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Plants & Animals
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Biotechnology
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Evolution
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