Related topics: host cell

Alternative CRISPR system is less specific, more robust

The genetic tool adept at line-by-line gene editing, CRISPR, has revolutionized the ability of scientists to manipulate genes for experimental, and perhaps someday therapeutic, purposes. But it comes in several varieties. ...

Researchers discover how CRISPR proteins find their target

Researchers at the University of California, Berkeley, have discovered how Cas1-Cas2, the proteins responsible for the ability of the CRISPR immune system in bacteria to adapt to new viral infections, identify the site in ...

A molecular on/off switch for CRISPR

Picture bacteria and viruses locked in an arms race. For many bacteria, one line of defense against viral infection is a sophisticated RNA-guided "immune system" called CRISPR-Cas. At the center of this system is a surveillance ...

Compact CRISPR systems found in some of world's smallest microbes

UC Berkeley scientists have discovered simple CRISPR systems similar to CRISPR-Cas9—a gene-editing tool that has revolutionized biology—in previously unexplored bacteria that have eluded efforts to grow them in the laboratory.

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