Using an approach based on CRISPR proteins, MIT researchers have developed a new way to precisely control the amount of a particular protein that is produced in mammalian cells.
Biotechnology
Nov 1, 2022
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28
Developing tools for precise control of biological processes has been one of the main pillars of the now mature field of synthetic biology. These scientific tools borrow principles from a multitude of research fields which, ...
Cell & Microbiology
Oct 5, 2022
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4
Northwestern Medicine investigators have discovered novel mechanisms underlying a specific transcription factor essential for elongation control, the process of synthesizing RNA from DNA, according to findings published in ...
Cell & Microbiology
Aug 11, 2022
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13
Tohoku University scientists in Japan have developed a virus-based approach for measuring variations in gene regulatory elements, called transcription factors, as conditions change in live organisms. The research, published ...
Molecular & Computational biology
Mar 18, 2022
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49
University of Toronto researchers have created a first-in-class functional catalog of proteins that activate gene expression, with implications for tailored therapy for cancer and other diseases that occur when wrong genes ...
Molecular & Computational biology
Feb 9, 2022
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92
There are many genes, or at least markers of one sort or another within our DNA sequences, that have been associated with height. By some estimates the number could be thousands. However, finding those select genes that have ...
"How does nature utilize the common repertoire of folds in proteins to differentiate their specificity, and ultimately their function?" This long-standing and fundamental question was addressed in a study conducted at the ...
Cell & Microbiology
Dec 7, 2021
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21
The rapid scientific advancements that followed the mapping of the human genome have revealed just how staggeringly complex the world of genetics is. We now know that proteins are not just the products of genes, but that ...
Molecular & Computational biology
Oct 27, 2021
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38
Scientists from Tokyo Metropolitan University have uncovered a unique mechanism where two transcription factors stabilize each other's binding to DNA in fission yeast. They found that Atf1 and Rst2 help each other stably ...
Molecular & Computational biology
Sep 13, 2021
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49
A gene called PfAP2-HS allows the malaria parasite to defend itself from adverse conditions in the host, including febrile temperatures, according to a new study led by the Barcelona Institute for Global Health (ISGlobal), ...
Cell & Microbiology
Aug 16, 2021
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