Scientists from Tokyo Metropolitan University have uncovered a unique mechanism where two transcription factors stabilize each other's binding to DNA in fission yeast. They found that Atf1 and Rst2 help each other stably ...
Molecular & Computational biology
Sep 13, 2021
0
49
A gene called PfAP2-HS allows the malaria parasite to defend itself from adverse conditions in the host, including febrile temperatures, according to a new study led by the Barcelona Institute for Global Health (ISGlobal), ...
Cell & Microbiology
Aug 16, 2021
0
108
Biochemists at Emory are achieving insights into how an important regulator of the immune system switches its function, based on its orientation and local environment. New research demonstrates that the glucocorticoid receptor ...
Biotechnology
Jul 22, 2021
0
167
Proteins known as transcription factors act as switches that regulate the expression of nearby genes, but the identity of some of these genetic levers has so far remained mysterious. Now, researchers from the Schübeler group ...
Biotechnology
Jul 8, 2021
0
30
Originally discovered as a bacterial mode of defense against invading viruses, the remarkable ability of CRISPR-Cas9 to modify specific locations of DNA has made it a researcher favorite among gene editing tools. The ongoing ...
Molecular & Computational biology
Jul 2, 2021
0
8
The genome of single-celled plankton, known as dinoflagellates, is organized in an incredibly strange and unusual way, according to new research. The findings lay the groundwork for further investigation into these important ...
Molecular & Computational biology
Apr 29, 2021
5
375
Plants in the bean family (legumes) form nodules on their roots to take up nitrogen. Legumes will stop nodule production when nitrogen is plentiful (Figure 1), but precisely how nitrate presence controls nodule formation ...
Molecular & Computational biology
Apr 9, 2021
0
11
A team led by scientists at the Perelman School of Medicine at the University of Pennsylvania has illuminated the functions of mysterious structures in cells called "nuclear speckles," showing that they can work in partnership ...
Molecular & Computational biology
Apr 5, 2021
0
595
Cells don't express all the genes they contain all the time. The portion of our genome that encodes eye color, for example, doesn't need to be turned on in liver cells. In plants, genes encoding the structure of a flower ...
Molecular & Computational biology
Jan 27, 2021
3
118
A joint research team from KAIST and UCSD has developed a deep neural network named DeepTFactor that predicts transcription factors from protein sequences. DeepTFactor will serve as a useful tool for understanding the regulatory ...
Molecular & Computational biology
Jan 5, 2021
0
13
