Scientists at Imperial College London have identified four new proteins that act as receptors for an essential signalling molecule in bacteria such as MRSA.
May 13, 2013
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Many proteins undergo extensive modification after being synthesized, particularly those that are secreted or embedded in the cell membrane. This is achieved within the Golgi apparatus (see image), a cellular ...
Apr 24, 2013
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(Phys.org) —Researchers at the University of Virginia School of Medicine have determined the molecular structure of a protein whose mutations have been linked to several early aging diseases, and to side effects of common ...
Apr 09, 2013
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Using a broad spectrum of analytical tools, scientists from the Florida campus of The Scripps Research Institute (TSRI) have uncovered a class of novel compounds that can alter cell signaling activity, resulting in a variety ...
Mar 26, 2013
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(Phys.org) —Patients who suffer from gingivitis are often advised to use disinfectant mouthwashes. In the future, the active ingredients in these products could be used in a completely different area: As ...
Mar 21, 2013
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For scientists to improve cancer treatments with targeted therapeutic drugs, they need to be able to see proteins prevalent in the cancer cells. This has been an impossible, until now. Thanks to a new microscopy ...
Feb 26, 2013
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A powerful computational technique used by the pharmaceutical industry to expedite new drug development has just received a performance boost. Chandra Verma and his co-workers at the A*STAR Bioinformatics ...
Jan 30, 2013
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(Phys.org)—A team of chemists and biologists led by Indiana University chemistry professor David Giedroc has described a previously unknown function of a protein they now know is responsible for protecting ...
Jan 29, 2013
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Scientists at the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), a part of the National Institutes of Health, have demonstrated that DNA previously thought to be "junk" plays a critical role ...
Dec 11, 2012
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Molecular chaperones have emerged as exciting new potential drug targets, because scientists want to learn how to stop cancer cells, for example, from using chaperones to enable their uncontrolled growth. ...
Dec 06, 2012
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Chromatin remodeling—the packaging and unpackaging of genomic DNA and its associated proteins—regulates a host of fundamental cellular processes including gene transcription, DNA repair, programmed cell ...
Nov 29, 2012
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Johns Hopkins scientists have discovered a new mode of action for enzymes immersed in cellular membranes. Their experiments suggest that instead of recognizing and clipping proteins based on sequences of ...
Nov 16, 2012
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Researchers at Tokyo Institute of Technology and the Weizmann Institute of Science identify a means of controlling biological processes that could help treatments for immune disease, neurological disorders ...
Nov 01, 2012
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Researchers at Johns Hopkins have figured out the three-dimensional shape of the protein responsible for creating unique bonds within the cell wall of the bacteria that cause tuberculosis. The bonds make ...
Oct 25, 2012
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Researchers from Johns Hopkins and Northwestern universities have discovered how to control the shape of nanoparticles that move DNA through the body and have shown that the shapes of these carriers may make ...
Oct 12, 2012
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