Historically, fly and human Polycomb proteins were considered textbook exemplars of transcriptional repressors, or proteins that silence the process by which DNA gives rise to new proteins. Now, work by a team of researchers ...
Cell & Microbiology
Apr 30, 2012
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(PhysOrg.com) -- A compound found in red wine, grapes and other fruits, and similar in structure to resveratrol, is able to block cellular processes that allow fat cells to develop, opening a door to a potential method to ...
Biochemistry
Apr 4, 2012
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Scientists seeking to improve cancer treatments have created a tiny drug transporter that maximizes its ability to silence damaging genes by finding the equivalent of an expressway into a target cell.
Bio & Medicine
Jul 26, 2011
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(Medical Xpress) -- McMaster researchers have discovered a new drug target that may be effective at preventing the onset of Huntington's disease, working much the same way heart medications slow the progression of heart disease ...
Biochemistry
May 31, 2011
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It's well known that the protein calmodulin specifically targets and steers the activities of hundreds of other proteins - mostly kinases - in our cells, thus playing a role in physiologically important processes ranging ...
Biochemistry
Aug 10, 2009
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UCSF scientists have created a method of quickly identifying large numbers of the genetic material known as short hairpin RNA — also called shRNA - that turns genes on and off.
Cell & Microbiology
May 19, 2009
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Investigators at Northwestern University have found that packing small interfering RNA (siRNA) molecules onto the surface of a gold nanoparticle can protect siRNAs from degradation and increase their ability to regulate genes ...
Bio & Medicine
Feb 23, 2009
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Cancer is a complex systemic disease, with accompanying secondary effects that can result in debilitating effects on the human body. Cancer-associated skeletal muscle weakening or loss, also called "cancer cachexia," is a ...
Bio & Medicine
Apr 24, 2023
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A review of gene editing techniques suggests that the CRISPR/Cas (clustered regularly interspaced short palindromic repeats/Cas) method could be a possible "savior" for rice crops threatened by climate change and high food ...
Biotechnology
Mar 3, 2023
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The Hirohide Saito Laboratory has developed cyclic RNA switches that can control gene expression in a cell type-specific manner using miRNAs and RNA-binding proteins and has successfully constructed an artificial gene circuit ...
Cell & Microbiology
Feb 16, 2023
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