The ability to translate the genetic code into proteins is an essential step in all living organisms. A cornerstone of this molecular process is the ability of transfer RNA (tRNA) molecules to couple recognition of the genetic ...
Molecular & Computational biology
Oct 19, 2018
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29
Scientists have long known that RNA encodes instructions to make proteins. The building blocks that comprise RNA—A, U, C, and Gs—form a blueprint for the protein-making machinery in cells. To make proteins, the machinery ...
Cell & Microbiology
Jul 16, 2018
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120
Ribosomes are organelles responsible for protein synthesis in all living organisms. Ribosomes are made of proteins and RNA (Ribosomal RNA, rRNA) and putting the several elements in the right location requires a precise multi-step ...
Cell & Microbiology
Apr 18, 2018
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2
A novel approach developed at the Friedrich Miescher Institute for Biomedical Research (FMI) has allowed scientists in Dirk Schübeler's group to dissect and quantify the individual steps of transcription initiation. Unexpectedly, ...
Cell & Microbiology
Jul 26, 2017
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15
Scientists at The Scripps Research Institute (TSRI) have solved a cellular mystery that may have important implications for fundamental biology and diseases like ALS. Their new research suggests that RNA may be the secret ...
Condensed Matter
Jun 13, 2017
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221
Control of RNA lifespan is vital for the proper functioning of our cells. Marc Bühler's group at the Friedrich Miescher Institute for Biomedical Research (FMI) has discovered a novel mechanism determining the fate of RNA ...
Cell & Microbiology
Jun 5, 2017
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12
Think of life as a house: if DNA molecules are blueprints, then messenger RNAs (mRNAs) are orders, describing the required parts (proteins) and when they should arrive. But putting in many orders doesn't always mean you'll ...
Biochemistry
May 3, 2017
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7
Protein synthesis is programmed by messenger RNAs, and when enough of a given protein has been made, the mRNAs that encode it are destroyed. LMU researchers have now shown that protein synthesis and mRNA degradation are structurally ...
Cell & Microbiology
Jan 26, 2017
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8
The ability to dispose of proteins that are either aberrant or (in the worst case) toxic is fundamental to a cell's survival. Researchers from Charité - Universitätsmedizin Berlin have been able to demonstrate the manner ...
Cell & Microbiology
Jan 19, 2017
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5
Ludwig Maximilian University of Munich researchers have elucidated a mechanism that recycles bacterial ribosomes stalled on messenger RNAs that lack termination codons. The protein involved provides a potential target for ...
Cell & Microbiology
Dec 5, 2016
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7
