Related topics: receptors · cells

Supercharged proteins enter biology's forbidden zone

Scientists are reporting discovery of a way to help proteins such as the new generation of protein-based drugs -- sometimes heralded as tomorrow's potential "miracle cures" -- get past the biochemical "Entrance Forbidden" ...

New molecule enables quick drug monitoring

Monitoring the drug concentration in patients is critical for effective treatment, especially in cases of cancer, heart disease, epilepsy and immunosuppression after organ transplants. However, current methods are expensive, ...

Modified caffeine molecules help medical research move forward

Before researchers can develop targeted drugs, they need to know exactly how a disease works. Biochemist Bert Beerkens created molecules that allow them to find out. He used caffeine as the basis for new molecules that enable ...

Mice with fewer insulin-signaling receptors don't live longer

Scientists studying longevity thought it might be good to lack a copy of a gene, called IGF1 receptor, that is important in insulin signaling. Previous studies showed invertebrates that lacked the copy lived longer, even ...

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