DNA 'spool' modification affects aging and longevity

Research on a modified protein around which DNA is wrapped sheds light on how gene regulation is linked to aging and longevity in nematodes, fruit flies and possibly humans.

Sugar key to cellular protein protection and viability

A Simon Fraser University laboratory's breakthrough in understanding how a specialized sugar regulates protein levels in our cells could generate new targets for therapies to treat diseases caused by improper protein regulation. ...

A first of its kind tool to study the histone code

University of North Carolina scientists have created a new research tool, based on the fruit fly, to help crack the histone code. This research tool can be used to better understand the function of histone proteins, which ...

New mechanism in gene regulation revealed

The information encoded in our genes is translated into proteins, which ultimately mediate biological functions in an organism. Messenger RNA (mRNA) plays an important role, as it is the molecular template used for translation. ...

Decoding mystery sequences involved in gene regulation

Every cell in an organism's body has the same copy of DNA, yet different cells do different things; for example, some function as brain cells, while others form muscle tissue. How can the same DNA make different things happen? ...

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