Harbingers of aging

Midlife crisis in the insect world: In a new study, Ludwig-Maximilians-Universitaet (LMU) in Munich researchers have detected age-dependent alterations in metabolism and gene regulation in middle-aged fruitflies, and show ...

Error correction strategies of cells: Team proposes new hypothesis

Cells dynamically respond to environmental signals by turning appropriate sets of genes on or off. The "control system" that determines which genes need to be expressed at what time depends primarily on the interactions between ...

Dually noted: New CRISPR-Cas9 strategy edits genes two ways

The CRISPR-Cas9 system has been in the limelight mainly as a revolutionary genome engineering tool used to modify specific gene sequences within the vast sea of an organism's DNA. Cas9, a naturally occurring protein in the ...

Batting practice in the genome

In the biochemical game of genetics, it was thought that the proteins controlling gene regulation in animals were either spectators or players.

Chromosome-folding theory shows promise

Human chromosomes are much bigger and more complex than proteins, but like proteins, they appear to fold and unfold in an orderly process as they carry out their functions in cells.

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