New human gene cluster sequence discovered

Investigators from the laboratory of Ali Shilatifard, Ph.D., the Robert Francis Furchgott Professor and chair of Biochemistry and Molecular Genetics, have discovered a new repeat gene cluster sequence that is exclusively ...

Researchers reveal universal mechanisms of DNA and RNA deformations

DNA and RNA, the two main types of nucleic acid and the building blocks of life, are susceptible to environmental stimuli, which can cause them to deform, bend or twist. These deformations can significantly affect gene regulation ...

Quantum machine shows promise for biological research

To date, much has been stated about the promise of quantum computing for myriad of applications but there have been few examples of a quantum advantage for real-world problems of practical interest. This might change with ...

Study uncovers the secrets of plant regeneration

Plants have the unique ability to regenerate entirely from a somatic cell, i.e., an ordinary cell that does not typically participate in reproduction. This process involves the de novo (or new) formation of a shoot apical ...

Decoding mystery sequences involved in gene regulation

Every cell in an organism's body has the same copy of DNA, yet different cells do different things; for example, some function as brain cells, while others form muscle tissue. How can the same DNA make different things happen? ...

Dually noted: New CRISPR-Cas9 strategy edits genes two ways

The CRISPR-Cas9 system has been in the limelight mainly as a revolutionary genome engineering tool used to modify specific gene sequences within the vast sea of an organism's DNA. Cas9, a naturally occurring protein in the ...

Researchers make important cell division discovery

Researchers at the University of Dundee have provided important new insights into the regulation of cell division, which may ultimately lead to a better understanding of cancer progression.

Scientists reveal how epigenetic changes in DNA are interpreted

A new study in Science from Karolinska Institutet maps out how different DNA-binding proteins in human cells react to certain biochemical modifications of the DNA molecule. The scientists report that some 'master' regulatory ...

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