RNA, once considered a bit player in the grand scheme by which genes encode protein, is increasingly seen to have a major role in human genetics. In a study presented in the April 25 issue of the journal Cell, researchers from T ...
May 01, 2013
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RNA molecules, made from DNA, are best known for their role in protein production. MicroRNAs (miRNAs), however, are short (~22) nucleotide RNA sequences found in plants and animals that do not encode pro ...
Apr 25, 2013
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Protein activity is strictly regulated. Incorrect or poor protein regulation can lead to uncontrolled growth and thus cancer or chronic inflammation. Members of the Institute of Veterinary Biochemistry and Molecular Biology ...
Mar 10, 2013
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A research team of scientists from the European Molecular Biology Laboratory of Grenoble and the Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC) in Strasbourg have now, for the first ...
Feb 05, 2013
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Whitehead Institute researchers have determined that DNA transcription, the process that produces messenger RNA (mRNA) templates used in protein production, also runs in the opposite direction along the DNA to create corresponding ...
Feb 04, 2013
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In each cell, thousands of regulatory regions control which genes are active at any time. Scientists at the Research Institute of Molecular Pathology (IMP) in Vienna have developed a method that reliably ...
Jan 18, 2013
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Berkeley Lab and UC Berkeley researchers have discovered that the transcription factor protein TFIID coexists in two distinct structural states, a key to genetic expression and TFIID's ability to initiate ...
Jan 17, 2013
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(Phys.org)—A research team of scientists from EMBL Grenoble and the IGBMC in Strasbourg, France, have, for the first time, described in molecular detail the architecture of the central scaffold of TFIID: the human protein ...
Jan 07, 2013
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(Phys.org)—Scientists at North Carolina State University have discovered a phenomenon never seen before in plants while studying molecular changes inside tree cells as wood is formed.
Aug 23, 2012
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(Phys.org) -- In a new study, UT Dallas researchers outline how they used fluorescent molecules to "tag" DNA and monitor a process called DNA looping, a natural biological mechanism involved in rearranging ...
Aug 13, 2012
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Regulation of gene expression is essential to make sure cell maturation occurs as it should. European research is taking an integrated perspective on how selected steps in liver and blood cell differentiation ...
Jul 16, 2012
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Molecular geneticists call big boss proteins that switch on broad developmental or metabolic programs "master regulators," as in master regulators of muscle development or fat metabolism. One such factor, ...
Jun 28, 2012
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(Phys.org) -- Genetic material has many inactive sections that are of major importance for cell identity and genome stability. The HP1 protein takes on key functions in shutting down such genomic sequences. ...
Jun 11, 2012
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In Alzheimer's disease, brain neurons become clogged with tangled proteins. Scientists suspect these tangles arise partly due to malfunctions in a little-known regulatory system within cells. Now, researchers have dramatically ...
Apr 16, 2012
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A team of geneticists and computational biologists in the UK today reveal how an ancient mechanism is involved in gene control and continues to drive genome evolution. The new study is published in the journal ...
Jan 12, 2012
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