Missing pathway in lysosome underlies newly discovered human disease
In a rare disease called mucolipidosis type II, people's hearts and abdomens swell, and their bones grow malformed.
In a rare disease called mucolipidosis type II, people's hearts and abdomens swell, and their bones grow malformed.
Cell & Microbiology
Oct 6, 2022
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102
The initiation of the innate immune responses relies on the detection of microbes by multiple pattern recognition receptors. Among these receptors, cyclic GMP-AMP synthase (cGAS) has been identified as a major and universal ...
Cell & Microbiology
Sep 8, 2022
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4
DNA double-strand breaks are one of the biggest threats to the genome and a driving force of carcinogenesis. Cellular repair mechanisms such as homologous recombination are essential for the maintenance of genome stability ...
Cell & Microbiology
Aug 24, 2022
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10
A new study from the University of Miami and University of Nebraska-Lincoln has upended decades of doctrine about an enzyme whose mutation or malfunction can trigger fatal diseases early in life. The research team, which ...
Biochemistry
Aug 18, 2022
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19
Researchers at the Institute of Modern Physics (IMP) of the Chinese Academy of Sciences (CAS), have made progress in the study of heavy ion mutagenesis breeding and the cellulase synthetic mechanism of enzyme-producing strains. ...
Biotechnology
Aug 2, 2022
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7
A chemical modification of messenger RNA (mRNA) performs different functions depending on its location, according to a study published in the journal Molecular Cell.
Cell & Microbiology
Jul 6, 2022
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7
Human saliva may contain an enzyme which can decompose the plastic polyethylene terephthalate (PET). Researchers found the promising enzyme, a hydrolase, in a database containing human metagenome samples. As they report in ...
Biochemistry
Jun 29, 2022
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691
Scientists are increasingly learning of new reasons to appreciate RNA, and the glycolytic enzyme ENO1 seems to have provided yet another in new research from EMBL this week, as published in Molecular Cell.
Cell & Microbiology
Jun 15, 2022
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34
Engineering enzymes to perform reactions not found in nature can address longstanding challenges in the world of synthetic chemistry, such as upgrading plant-based oils into useful biochemicals.
Biochemistry
May 2, 2022
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77
The pathogen Acinetobacter baumannii can survive on hospital surfaces—without water—for months, an ability that has helped it become a leading cause of hospital-acquired infections.
Cell & Microbiology
May 2, 2022
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103