A new study in Nature reports an AI-driven advance in biotechnology with implications for drug development, disease detection, and environmental monitoring. Scientists at the Institute for Protein Design at the University ...
Biotechnology
Dec 18, 2023
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85
Most diseases are caused by proteins that have spun out of control. Unfortunately, so far, conventional drugs have been able to stop only a fraction of these troublemakers. A new class of drugs known as PROTACs holds great ...
Biochemistry
Dec 11, 2023
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57
While we often think of diseases as caused by foreign bodies—bacteria or viruses—there are hundreds of diseases affecting humans that result from errors in cellular production of proteins.
Cell & Microbiology
Dec 4, 2023
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323
Scientists at the University of Bath have used nature as inspiration in developing a new tool that will help researchers develop new pharmaceutical treatments in a cleaner, greener, and less expensive way.
Biochemistry
Nov 28, 2023
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42
Methamphetamine (meth) abuse is a major health concern. Understanding how meth interacts with its target proteins is crucial for the development of novel medications to address drug addiction. Previous research into the mechanism ...
Biochemistry
Nov 24, 2023
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53
A new study from the University of Eastern Finland shows that the delivery of drugs into the brain, and especially into glial cells, can be enhanced with prodrugs that temporarily incorporate thyroxine or a thyroxine-like ...
Biochemistry
Nov 8, 2023
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45
A detailed atomic exploration into how the dengue virus replicates its genome could catalyze the development of high-precision targeted antiviral therapeutics.
Cell & Microbiology
Oct 31, 2023
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1
Researchers at the Icahn School of Medicine at Mount Sinai have identified the structure of a special transporter found in red blood cells and how it interacts with drugs. Details on the findings, which were reported in the ...
Molecular & Computational biology
Sep 7, 2023
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81
Membrane proteins play a pivotal role in various cellular functions and are key targets for pharmaceutical interventions. In fact, approximately 60% of drugs currently available on the market target these specific proteins. ...
Molecular & Computational biology
Sep 7, 2023
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1
Human cells are protecting their proteins from unfolding and aggregating. That's what biophysicist Alireza Mashaghi and his team discovered after seven years of in-depth research into the folding mechanisms of proteins. With ...
Molecular & Computational biology
Aug 1, 2023
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235
