Simplified method makes cell-free protein synthesis more flexible and accessible
Researchers have radically simplified the method for cell-free protein synthesis (CFPS), a technique that could become fundamental to medical research.
Researchers have radically simplified the method for cell-free protein synthesis (CFPS), a technique that could become fundamental to medical research.
Biochemistry
Feb 25, 2019
0
17
Researchers at the University of Helsinki uncovered the mechanisms for a novel cellular stress response arising from the toxicity of newly synthesized proteins. Activation of the stress response is at the epicentre of the ...
Cell & Microbiology
Feb 22, 2019
0
2
Nonsense mutations are single-letter errors in the genetic code that prematurely halt the production of critical proteins. These unfinished proteins are unable to function normally, and nonsense mutations cause 10-15 percent ...
Molecular & Computational biology
Feb 19, 2019
0
45
Today, thousands of databases with biological data are publicly available. They include data on gene and protein sequences and detailed measurements of different cellular parameters, such as the exact quantities of all proteins ...
Cell & Microbiology
Feb 5, 2019
0
42
The human genome contains regions that "code" for proteins, which means they have instructions to make protein molecules with specific functions in the body. But Yale researchers have discovered several protein-coding genes ...
Molecular & Computational biology
Dec 13, 2018
0
40
In recent years, scientists have engineered bacteria with expanded genetic codes that produce proteins made from a wider range of molecular building blocks, opening up a promising front in protein engineering.
Biochemistry
Nov 28, 2018
0
20
Since the time of ancient Egypt, humans have been making and breaking secret codes to retain and gain critical information. Human life itself is based upon a genetic code of DNA or RNA sequences which cells read and translate ...
Biochemistry
Nov 8, 2018
0
16
A Danish research team has delineated a complex symbiosis between a 'parasitic' noncoding RNA gene and its protein-coding 'host' gene in human cells. The study reveals how co-evolution of the host gene and parasite gene has ...
Cell & Microbiology
Sep 20, 2018
0
16
Accumulating evidence suggests that new genes can arise spontaneously from previously non-coding DNA instead of through the gradual mutation of established genes. Bioinformaticians at the University of Münster (Germany) ...
Evolution
Sep 12, 2018
0
101
A biological switch that reliably turns protein expression on at will has been invented by University of Bath and Cardiff University scientists. The switch enables control of genome editing tools that might one day regulate ...
Biotechnology
Jul 3, 2018
0
106