Understanding the behavior of proteins and enzymes is key to unlocking the secrets of biological processes. The atomic structures of proteins are generally investigated using X-ray crystallography; however, the precise information ...
General Physics
Apr 27, 2020
0
155
One of the key features in the evolution of more complex organisms is the emergence of allosteric regulation. Allostery is a process by which a protein's activity can be modulated by binding an effector molecule distal to ...
Biochemistry
Feb 24, 2020
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27
To disarm toxic substances, many organisms including humans possess enzymes called flavin-containing monooxygenases (FMOs). Despite their importance, the structure of the enzymes has not been resolved, as the protein is too ...
Evolution
Dec 23, 2019
0
133
EPFL scientists have developed a computational method modeling and designing protein allostery that allows the accurate and rational engineering and even repurposing of cell receptors. The method can be a significant tool ...
Biochemistry
Dec 2, 2019
0
36
Amid the zoo of biomolecules essential to life, enzymes are among the most vital. Without these specialized proteins, which speed up the rates of chemical reactions, thousands of essential life processes, from cell growth ...
Bio & Medicine
Oct 31, 2019
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437
Zoë Fisher and Katarina Koruza from the ESS Deuteration and Macromolecular Crystallization (DEMAX) Support lab and Lund University have been using vapor diffusion methods to grow large protein crystals for neutron techniques ...
Materials Science
Oct 1, 2019
0
14
They say love is blind, but if you're a queen honeybee it could mean true loss of sight.
Plants & Animals
Sep 10, 2019
1
778
Builders of genetic circuits face the same quandary as builders of digital circuits: testing their designs. Yet unlike bioengineers, engineers have a simple and universal testing tool—the multimeter—that they can touch ...
Molecular & Computational biology
May 21, 2019
0
104
Johns Hopkins researchers have discovered a long-sought protein, the proton-activated chloride channel (PAC), that is activated in acidic environments and could protect against the tissue-damaging effects of stroke, heart ...
Evolution
May 20, 2019
0
13
IMP scientists from the lab of Alexander Stark show why certain activators—enhancers or cofactor proteins—activate specific promoters. The findings, which are now reported in the journal Nature, could have implications ...
Biotechnology
May 16, 2019
0
83
