New mechanism for anti-infection effects of dietary fiber

New research in mice has uncovered a previously unknown interaction between molecules derived from dietary fiber and an immune cell protein, which triggers protection against infection with Salmonella bacteria. Hitoshi Tsugawa ...

Research reveals how wounds heal in 'waves'

Many cells in our bodies are on the move and somehow seem to 'know' where to go. But how do they learn the location of their destination? This question is key to understanding phenomena such as the renewal of cells in our ...

Biophysicists reveal how optogenetic tool works

An international research team has for the first time obtained the structure of the light-sensitive sodium-pumping KR2 protein in its active state. The discovery provides a description of the mechanism behind the light-driven ...

Lysosome to mitochondria communication regulates longevity

As people get older, they often feel less energetic, mobile or active. This may be due in part to a decline in mitochondria, the tiny powerhouses inside of our cells, which provide energy and regulate metabolism. In fact, ...

It takes a neutron beam to find a proton

Understanding the behavior of proteins and enzymes is key to unlocking the secrets of biological processes. The atomic structures of proteins are generally investigated using X-ray crystallography; however, the precise information ...

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