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News tagged with oncogene

Cancer: 'Primitive' gene discovered

To find the causes for cancer, biochemists and developmental biologists at the University of Innsbruck, Austria, retraced the function of an important human cancer gene 600 million years back in time. For ...

Medicine & Health / Cancer

created Feb 11, 2010 | popularity 5 / 5 (7) | comments 0 | with audio podcast

Researchers make major breakthrough in melanoma research

In a breakthrough that could lead to new treatments for patients with malignant melanoma, researchers from Mount Sinai School of Medicine have discovered that a particular protein suppresses the progression of melanoma through ...

Medicine & Health / Cancer

created Dec 22, 2010 | popularity 5 / 5 (6) | comments 0 | with audio podcast

Scientists discover first breast cancer 'oncogene' in five years

(PhysOrg.com) -- Scientists have pinpointed a key cancer-causing gene that, when overactive, triggers a particularly aggressive type of breast cancer to develop.

Medicine & Health / Cancer

created Feb 18, 2011 | popularity 5 / 5 (6) | comments 0 | with audio podcast

Suppressing activity of common intestinal bacteria reduces tumor growth

A team of University of California, San Diego School of Medicine researchers has discovered that common intestinal bacteria appear to promote tumor growths in genetically susceptible mice, but that tumorigenesis can be suppressed ...

Medicine & Health / Cancer

created May 09, 2010 | popularity 4.8 / 5 (6) | comments 3 | with audio podcast

New melanoma tumor suppressor gene uncovered

National Institutes of Health (NIH) researchers have identified a gene that suppresses tumor growth in melanoma, the deadliest form of skin cancer. The finding is reported today in the journal Nature Genetics as part of a s ...

Medicine & Health / Genetics

created Mar 29, 2009 | popularity 4 / 5 (5) | comments 2

Cancer-causing bacterium targets tumor-suppressor protein

Researchers have discovered a mechanism by which Helicobacter pylori, the only known cancer-causing bacterium, disables a tumor suppressor protein in host cells.

Medicine & Health / Cancer

created Aug 02, 2010 | popularity 5 / 5 (4) | comments 0 | with audio podcast

UA Researcher Awarded Patent for Breast Cancer Drug Breakthrough

(PhysOrg.com) -- The treatment is designed to block the interaction of two proteins in cells that cause breast cancer to grow and spread. It targets cancer-specific interactions and has shown no toxicity to normal cells ...

Medicine & Health / Cancer

created Aug 19, 2010 | popularity 5 / 5 (4) | comments 1

Blocking an oncogene in liver cancer could be potential therapy option

Scientists have found that a synthetic molecule they designed can block activation of a gene in liver cancer cells, halting a process that allows some of those cancer cells to survive chemotherapy.

Chemistry / Biochemistry

created Oct 12, 2010 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Gene may be good target for tough-to-kill prostate cancer cells

Purdue University scientists believe they have found an effective target for killing late-stage, metastatic prostate cancer cells.

Chemistry / Biochemistry

created Sep 27, 2011 | popularity 5 / 5 (3) | comments 0 | with audio podcast

New Hope for Deadly Childhood Bone Cancer

(PhysOrg.com) -- Researchers at Huntsman Cancer Institute (HCI) at the University of Utah have shed new light on Ewing’s sarcoma, an often deadly bone cancer that typically afflicts children and young adults. Their research ...

Medicine & Health / Cancer

created Aug 31, 2009 | popularity 5 / 5 (2) | comments 0

New research shows versatility of amniotic fluid stem cells

For the first time, scientists have demonstrated that stem cells found in amniotic fluid meet an important test of potential to become specialized cell types, which suggests they may be useful for treating a wider array of ...

Medicine & Health / Medical research

created Nov 23, 2009 | popularity 5 / 5 (2) | comments 0

Study sheds light on role of stem cells in children's brain tumor

(PhysOrg.com) -- New research from scientists at Queen Mary, University of London shows how the most common type of children's brain cancer can arise from stem cells.

Medicine & Health / Cancer

created Jan 11, 2010 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Roundworm unlocks pancreatic cancer pathway

The National Cancer Institute estimates that more than 43,000 Americans were diagnosed with pancreatic cancer last year and more than 36,000 died from the disease. Despite advances in genetic science showing that the Ras ...

Medicine & Health / Cancer

created Jan 19, 2011 | popularity 5 / 5 (2) | comments 0

Study unmasks a stem cell origin of skin cancer and the genetic roots of malignancy

A constellation of different stem cell populations within our skin help it to cope with normal wear and tear. By constantly proliferating, the stem cells allow skin to replenish itself, allowing each cell to be replaced by ...

Medicine & Health / Cancer

created Feb 03, 2011 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Study Describes Novel Model of Skin Cancer

(PhysOrg.com) -- Scientists at the University of Pennsylvania School of Medicine have developed a new model of skin cancer based on the knowledge that a common cancer-related molecule called Src kinase is ...

Medicine & Health / Cancer

created Dec 09, 2009 | popularity 4.5 / 5 (2) | comments 0

Oncogene

An oncogene is a gene that, when mutated or expressed at high levels, helps turn a normal cell into a cancer cell.

Many cells normally undergo a programmed form of death (apoptosis). Activated oncogenes can cause those cells to survive and proliferate instead. Most oncogenes require an additional step, such as mutations in another gene, or environmental factors, such as viral infection, to cause cancer. Since the 1970s, dozens of oncogenes have been identified in human cancer. Many cancer drugs target those DNA sequences and their products.

For more information about Oncogene, read the full article at Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.