Stem cells play a critical role in replacing various cells within the intestine, but can also become drivers for colorectal cancer. The composition of these stem cell reservoirs has been debated. New research from Dmitry ...
Cell & Microbiology
Aug 14, 2013
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Historically, fly and human Polycomb proteins were considered textbook exemplars of transcriptional repressors, or proteins that silence the process by which DNA gives rise to new proteins. Now, work by a team of researchers ...
Cell & Microbiology
Apr 30, 2012
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Scientists have found that a synthetic molecule they designed can block activation of a gene in liver cancer cells, halting a process that allows some of those cancer cells to survive chemotherapy.
Biochemistry
Oct 12, 2010
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(PhysOrg.com) -- Research in the worm is shedding light on a protein associated with a number of different human cancers, and may point to a highly targeted way to treat them.
Cell & Microbiology
Apr 21, 2011
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(Phys.org)—Purdue University scientists have determined that a gene long known to be involved in cancer cell formation and chemotherapy resistance is key to proper RNA creation, an understanding that could one day lead ...
Biochemistry
Sep 12, 2012
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Researchers have devised a scheme for identifying genes in yeast that could lead to the identification of new cancer genes in humans. The study is published online this week in the open-access journal PLoS Biology.
Biotechnology
Jul 28, 2009
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Purdue University scientists believe they have found an effective target for killing late-stage, metastatic prostate cancer cells.
Biochemistry
Sep 27, 2011
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One of the most frustrating problems faced by doctors who treat pancreatic cancer is the lack of effective therapeutic options. More than 38,000 people in the United States die of the disease each year, and new drugs and ...
Biochemistry
Nov 5, 2010
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0
The discovery that a protein called Rictor plays a key role in destroying a close cousin of the AKT oncogene could provide scientists with a new molecular target for treating certain cancers, including breast cancer. Described ...
Cell & Microbiology
Oct 28, 2010
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Northwestern Medicine scientists have invented a new method for resolving rearranged chromosomes and their 3D structures in cancer cells, which can reveal key gene regulators that lead to the development of tumors, published ...
Biotechnology
Jun 10, 2021
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An oncogene is a gene that, when mutated or expressed at high levels, helps turn a normal cell into a cancer cell.
Many cells normally undergo a programmed form of death (apoptosis). Activated oncogenes can cause those cells to survive and proliferate instead. Most oncogenes require an additional step, such as mutations in another gene, or environmental factors, such as viral infection, to cause cancer. Since the 1970s, dozens of oncogenes have been identified in human cancer. Many cancer drugs target those DNA sequences and their products.
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