The genetic material of each mammalian cell is safeguarded within the cell's nucleus. In healthy organisms, the usually round-shaped nucleus gets its stability from the nuclear envelope and the nuclear lamina. The latter ...
Cell & Microbiology
Oct 1, 2019
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36
Multiple components of the nuclear pore complex and nuclear import machinery enable a protein called human myxovirus resistance 2 (MX2) to inhibit HIV-1 infection, according to a study published November 29 in the open-access ...
Cell & Microbiology
Nov 29, 2018
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16
Like an island nation, the nucleus of a cell has a transportation problem. Evolution has enclosed it with a double membrane, the nuclear envelope, which protects DNA but also cuts it off from the rest of the cell. Nature's ...
Cell & Microbiology
Mar 15, 2018
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126
A team of scientists has revealed an internal clock within live human cells, a finding that creates new opportunities for understanding the building blocks of life and the onset of disease.
General Physics
Sep 11, 2017
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2159
Susan Gasser and her group at the FMI have identified in C. elegans a much sought-for anchor protein, a previously uncharacterized chromodomain protein called CEC-4 that directly sequesters inactive chromatin at the nuclear ...
Cell & Microbiology
Dec 2, 2015
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409
Sometimes, the molecules that make up life exhibit strange behavior. For instance, in simple organisms such as yeast, when genetic material becomes damaged, the affected DNA strands increase their motion, waving about inside ...
Cell & Microbiology
Nov 5, 2015
16
81
Not just anything is allowed to enter the nucleus, the heart of eukaryotic cells where, among other things, genetic information is stored. A double membrane, called the nuclear envelope, serves as a wall, protecting the contents ...
Biochemistry
Aug 27, 2015
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3197
(Phys.org) —Proteins known as histones give structure to DNA, which coils around them like string on spools. But as is so often the case in biology, it turns out there is more to these structures than meets the eye. Scientists ...
Cell & Microbiology
Sep 25, 2014
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0
Researchers at the Stowers Institute for Medical Research have glimpsed two proteins working together inside living cells to facilitate communication between the cell's nucleus and its exterior compartment, the cytoplasm. ...
Cell & Microbiology
Feb 10, 2014
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0
Our genetic heritage is contained—and protected—in the nucleus of the cells that compose us. Copies of the DNA exit the nucleus to be read and translated into proteins in the cell cytoplasm. The transit between the nucleus ...
Cell & Microbiology
Sep 27, 2013
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