News tagged with mouse model

Related topics: stem cells , cancer cells , cells , immune cells , animal model

Magnetic nanochain detonates chemo barrage inside tumors

Medicine-toting nanochains slip into tumors and explode a chemotherapy drug into hard-to-reach cores of cancer, engineers and scientists at Case Western Reserve University report.

Nanotechnology / Bio & Medicine

created Apr 18, 2012 | popularity 5 / 5 (8) | comments 0 | with audio podcast

A new shortcut for stem cell programming

Scientists at the Life and Brain Research Center at the University of Bonn, Germany, have succeeded in directly generating brain stem cells from the connective tissue cells of mice.

Biology / Cell & Microbiology

created Mar 22, 2012 | popularity not rated yet | comments 0

Cure of ADPKD by selection for spontaneous genetic repair events in Pkd1-mutated iPS cells

A research group including Kyoto University researchers demonstrates that mouse iPS cells, in which genetic correction occurs spontaneously through mitotic recombination, is selectable from the population of genetically mutated ...

Biology / Cell & Microbiology

created Feb 10, 2012 | popularity 5 / 5 (1) | comments 0

Gold nanorods could improve radiation therapy of head and neck cancer

Radiation therapy is an important part of head and neck cancer therapy, but most head and neck tumors have a built-in mechanism that makes them resistant to radiation. As a result, oncologists have to deliver huge doses of ...

Nanotechnology / Bio & Medicine

created Jan 20, 2012 | popularity 5 / 5 (3) | comments 1 | with audio podcast

Scientists combine tumor-targeting peptides and nanoparticles to destroy glioblastoma

Glioblastoma is one of the most aggressive forms of brain cancer. Rather than presenting as a well-defined tumor, glioblastoma will often infiltrate the surrounding brain tissue, making it extremely difficult to treat surgically ...

Nanotechnology / Bio & Medicine

created Oct 03, 2011 | popularity 5 / 5 (6) | comments 4 | with audio podcast

Autistic mice act a lot like human patients

UCLA scientists have created a mouse model for autism that opens a window into the biological mechanisms that underlie the disease and offers a promising way to test new treatment approaches.

Biology / Cell & Microbiology

created Sep 29, 2011 | popularity 5 / 5 (2) | comments 0

Mouse genetic blueprint developed

Researchers have developed a valuable mouse genetic blueprint that will accelerate future research and understanding of human genetics. The international team, led by researchers at the Wellcome Trust Sanger ...

Biology / Biotechnology

created Sep 14, 2011 | popularity not rated yet | comments 0 | with audio podcast

'Dirty' wild mice may be more relevant immunology model

Like humans, mice that live in their natural habitat encounter bacteria and other pathogens that exercise their immune system, yet the lab mice typically used in immunology studies are raised in isolation from most diseases. ...

Biology / Ecology

created Sep 08, 2011 | popularity 5 / 5 (1) | comments 1

Human-cell-derived model of ALS provides a new way to study the majority of cases

For decades, scientists have studied a laboratory mouse model that develops signs of the paralyzing disease amyotrophic lateral sclerosis (ALS) as they age. In a new study appearing in Nature Biotechnology, investigators at Nat ...

Biology / Biotechnology

created Aug 11, 2011 | popularity not rated yet | comments 0 | with audio podcast

Leftover embryonic cells connect gastric reflux and cancer

The ultimate source of some cancers is embryonic cells. Research published in the June 24th Cell, a Cell Press publication, traces the precursor of deadly esophageal cancers to leftover embryonic cells found in all adults ...

Biology / Cell & Microbiology

created Jun 23, 2011 | popularity not rated yet | comments 0

Aurora A may contribute to kidney disease

The Aurora A kinase may contribute to polycystic kidney disease (PKD) by inactivating a key calcium channel in kidney cells, according to a study in the June 13 issue of The Journal of Cell Biology.

Biology / Cell & Microbiology

created Jun 13, 2011 | popularity not rated yet | comments 0

Led by advances in chemical synthesis, scientists find natural product shows pain-killing properties

Scientists from the Florida campus of The Scripps Research Institute have for the first time accomplished a laboratory synthesis of a rare natural product isolated from the bark of a plant widely employed in traditional medicine. ...

Chemistry / Biochemistry

created May 23, 2011 | popularity 5 / 5 (2) | comments 3 | with audio podcast

Subset of self-destructive immune cells may selectively drive diabetes

New research identifies a distinctive population of immune cells that may play a key role in the pathogenesis of diabetes. The research, published by Cell Press and available online in the April 21st issue of Immunity, sheds ...

Medicine & Health / Medical research

created Apr 21, 2011 | popularity 5 / 5 (1) | comments 0

Antibiotics disrupt gut ecology, metabolism

(PhysOrg.com) -- Humans carry several pounds of microbes in our gastro-intestinal tracts. Recent research suggests that this microbial ecosystem plays a variety of critical roles in our health. Now, working in a mouse model, ...

Medicine & Health / Medical research

created Apr 20, 2011 | popularity not rated yet | comments 0

Tinnitus caused by too little inhibition of brain auditory circuits, study says

Tinnitus, a relentless and often life-changing ringing in the ears known to disable soldiers exposed to blasts, unwary listeners of too-loud music and millions of others, is the result of under-inhibition of key neural pathways ...

Medicine & Health / Medical research

created Apr 18, 2011 | popularity 5 / 5 (3) | comments 11 | with audio podcast