Inasmuch as therapeutic options against coronavirus have been focused mainly on blocking the interaction between its spike protein and the ACE2 receptor on host cells, SARS-CoV-2 has several additional critical proteins that ...
The crystal structure of a human endogenous reverse transcriptase has similarities to HIV reverse transcriptase, a well-known tractable drug target, which will help design drugs to treat cancer and other diseases, according ...
Biochemistry
Jun 30, 2022
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43
When an HIV outbreak hit Indiana's rural Scott County in 2015, the sparsely staffed health department was stretched to confirm cases among an entire community with lab tests that aren't portable and could take weeks to return ...
Analytical Chemistry
Feb 5, 2019
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29
(Phys.org) —A multidisciplinary team of scientists from UCLA and Stanford University has used a naturally occurring nanoparticle called a vault to create a novel drug delivery system that could lead to advances in the treatment ...
Bio & Medicine
Aug 22, 2014
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1
In recent research published in the Journal of Biological Chemistry, Saint Louis University investigators report catching integrase, the part of retroviruses like HIV that is responsible for insertion of the viral DNA into ...
Biochemistry
Aug 6, 2014
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0
A proof-of-concept experiment has shown that, by shifting evolution into reverse, it may be possible to use 'green chemistry' to make a number of costly synthetic drugs as easily and cheaply as brewing beer.
Biochemistry
Mar 23, 2014
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0
A collaborative team led by a Northeastern University professor may have altered the way we look at drug development for HIV by uncovering some unusual properties of a human protein called APOBEC3G (A3G).
Biochemistry
Nov 25, 2013
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0
(Phys.org) —In a study published in today's issue of Nature Communications, researchers from FIU's Herbert Wertheim College of Medicine describe a revolutionary technique they have developed that can deliver and fully release ...
Bio & Medicine
Apr 17, 2013
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0
The human immunodeficiency virus (HIV) can contain dozens of different mutations, called polymorphisms. In a recent study an international team of researchers, including MU scientists, found that one of those mutations, called ...
Biochemistry
Sep 13, 2012
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0
Policymakers struggling to stop the spread of HIV grapple with "what if" questions on the scale of millions of people and decades of time. They need a way to predict the impact of many potential interventions, alone or in ...
Computer Sciences
Jul 27, 2012
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