News tagged with histones

The importance of mixed motifs

Local modifications in histone proteins alter DNA packing density in the cell nucleus to regulate gene activity. They also form the basis of a code in which the significance of a given pattern or motif depends on its broader ...

dateJan 28, 2016 in Biotechnology
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Packaging and unpacking of the genome

DNA represents a dynamic form of information, balancing efficient storage and access requirements. Packaging approximately 1.8m of DNA into something as small as a cell nucleus is no mean feat, but unpacking it again to access ...

dateNov 06, 2015 in Biotechnology
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New tool brings standards to epigenetic studies

One of the most widely used tools in epigenetics research - the study of how DNA packaging affects gene expression - is chromatin immunoprecipitation (ChIP), a technique that allows researchers to examine interactions between ...

dateJun 04, 2015 in Biotechnology
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Decoding the cell's genetic filing system

A fully extended strand of human DNA measures about five feet in length. Yet it occupies a space just one-tenth of a cell by wrapping itself around histones—spool-like proteins—to form a dense hub of information called ...

dateApr 22, 2015 in Biochemistry
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