High vinculin levels help keep aging fruit fly hearts young

Our cells tend to lose their shape as we grow older, contributing to many of the effects we experience as aging. This poses particular problems for the heart, where aging can disrupt the protein network within muscle cells ...

Exercise has benefits, even when it's done in space

Astronauts have been taking part in short spaceflight missions since 1961. They have only recently begun to spend significantly longer times in space, with missions extending for months, since the days of the Russian Mir ...

Computer simulations reveal the energy landscape of ion channels

Every cell of our body is separated from its environment by a lipid bilayer. In order to maintain their biological function and to transduce signals, special proteins, so called ion channels, are embedded in the membrane. ...

And the beat goes on: The reliable heartbeat of hibernators

At the current temperatures, all hibernators have probably emerged from their winter hibernation and are enjoying the warm weather. However, this is quite different during the cold season. Many small mammals such as marmots, ...

Genetic defect leads to motor disorders in flies

In their study, the research groups looked at a protein called Creld. A study from Bonn had recently been able to demonstrate that Creld plays an important role in the development of the heart in mammals. "We wanted to find ...

Scavengers "protect" HDL

High-density lipoprotein (HDL) is widely thought to protect against the development of atherosclerosis, yet drugs that raise levels of HDL cholesterol (HDL-C) have failed to reduce the risk of heart disease.

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