New machine learning technology explores circadian rhythms

We all have an internal clock but what makes us tick? Scientists at the Earlham Institute and IBM Research have developed new artificial intelligence (AI) and machine learning (ML) technology to understand how gene expression ...

A new signaling pathway for mTor-dependent cell growth

The activation of mTor complex 1 in the cell is central to many vital processes in the body such as cell growth and metabolism. Overactivity of this signaling pathway can result in diseases such as in diabetic insulin resistance ...

How to make healthy buildings in an era of mass migration

Worldwide population growth and mass migrations are putting the infrastructure of many cities under strain. With city governments under pressure to provide more housing and work spaces, people can end up living and working ...

How intracellular signaling regulates growth factor production

Cancer cells need life-essential molecules to proliferate. These so-called growth factors are activated by ectodomain shedding of precursor proteins on the outside of the plasma membrane, mainly carried out by three human ...

New way to target 'undruggable' molecules involved in cancer

For decades, cancer researchers have longed for a way to target a set of proteins called transcription factors. While we've long known that tumors use these proteins to grow out of control, their unique configurations meant ...

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