Divide and define: Clues to understanding how stem cells produce different kinds of cells
The human body contains trillions of cells, all derived from a single cell, or zygote, made by the fusion of an egg and a sperm. That single cell contains all the genetic information needed to develop into ...
Threaded through a pore: Single-molecule detection of hydroxymethylcytosine in DNA
(Phys.org) —Changes in the bases that make up DNA act as markers, telling a cell which genes it should read and which it shouldn't. In the journal Angewandte Chemie, a British team has now introduced a new ...
Researchers study code that allows bacteria to either bet on the present or travel in time
(Phys.org)—Individual freedom and social responsibility may sound like humanistic concepts, but an investigation of the genetic circuitry of bacteria suggests that even the simplest creatures can make difficult choices ...
Reverse extinction: Should we redo the dodo?
Woolly mammoths stomp through the Siberian tundra as the giant moa strides the forest floor of New Zealand and Tasmania's dog-like "tigers" stalk their prey under the cover of night. This is not a snapshot ...
Head-on collisions between DNA-code reading machineries accelerate gene evolution
Bacteria appear to speed up their evolution by positioning specific genes along the route of expected traffic jams in DNA encoding. Certain genes are in prime collision paths for the moving molecular machineries ...
How proteins read meta DNA code
Three-quarters of the DNA in evolved organisms is wrapped around proteins, forming the basic unit of DNA packaging called nucleosomes, like a thread around a spool. The problem lies in understanding how DNA can then be read ...
First tapeworm genomes give insights into parasite evolution
Tapeworms have no gut or head. They are parasites that cause debilitating diseases, which can be deadly and often don't respond to drugs. Now, scientists have mapped the genetic code of tapeworms for the ...
Viruses: More survival tricks than previously thought
Among eukaryotes with modified nuclear genetic codes, viruses are unknown. Until now it had been believed that the modifications to the genetic code effectively prevented new viral infections. However, researchers have now ...
Analytical trick accelerates protein studies
Researchers at the University of Wisconsin-Madison have found a new way to accelerate a workhorse instrument that identifies proteins. The high-speed technique could help diagnose cancer sooner and point to new drugs for ...
When it comes to genetic code, researchers prove optimum isn't always best
Imagine two steel springs identical in look and composition but that perform differently because each was tempered at a different rate.
'Snooze button' on biological clocks improves cell adaptability
The circadian clocks that control and influence dozens of basic biological processes have an unexpected "snooze button" that helps cells adapt to changes in their environment.
Graduate student invents new cancer drug delivery vehicle
(Phys.org)—Sean Hemp of Raleigh, N.C., a Ph.D. student in chemistry in the College of Science, is helping to invent new therapies that target genetic disease and cancer.
Starchy genes made dog into Man's best friend, study reports
The question of how some wolves evolved into the trusty dogs that work on farms, lead the blind and curl up on pillows in bedrooms has remained largely unanswered. Until now.
A hidden genetic code: Researchers identify key differences in seemingly synonymous parts of the structure
Harvard scientists say they've solved a mystery that's nearly as old as science's understanding of the genetic code.