Related topics: cells · mouse model · virus · genes · cancer cells

How bacteria evade bacteriophages in vivo

Phage therapy, which uses viruses known as bacteriophages to treat bacterial infections, is a long-standing medical procedure whose mechanisms of action are still poorly understood. Scientists from the Institut Pasteur and ...

'Unassuming' enzyme opens way for new medical treatments

It sounds like a plot for a Cold War thriller—training a gene to infiltrate a cell and reside there, unnoticed, until an external self-destruct signal induces it to destroy its new home.

Landing therapeutic genes safely in the human genome

Many future gene and cell therapies to treat diseases like cancer, rare genetic and other conditions could be enhanced in their efficacy, persistence, and predictability by so-called "genomic safe harbors (GSHs)." These are ...

Bacterial viruses: Faithful allies against antibiotic resistance

It is a fact that bacteria are increasingly developing antibiotic resistance. Information campaigns have raised awareness among the general public that the main cause of antibiotic resistance is the high 'selection pressure' ...

Treatment with gene therapy of a new rat model of Morquio A

A research team from the Universitat Autònoma de Barcelona (UAB) has generated the first rat model recapitulating all disabling alterations experienced by patients with Mucopolysaccharidosis type IVA, also known as Morquio ...

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