Scientists from the Florida campus of The Scripps Research Institute (TSRI) have described a pair of drug candidates that advance the search for new treatments for pain, addiction and other disorders.
Biochemistry
Jan 13, 2014
0
0
A small molecule earlier found to have both anti-fat and anti-cancer abilities works as a literal turnoff for fat-making genes, according to a new report in the August 28th issue of the journal Chemistry and Biology, a Cell ...
Biochemistry
Aug 27, 2009
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0
A research team of pharmacists at the University of Bonn has discovered two families of active substances that can block the replication of the SARS-CoV-2 coronavirus. The drug candidates are able to switch off the the key ...
Biochemistry
Mar 3, 2021
1
66
It's difficult and time-consuming to produce accurate computer models of molecules, primarily because traditional modeling methods are limited in their ability to handle alternative molecular shapes and, consequently, are ...
Cell & Microbiology
Sep 26, 2013
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0
Scientists at Trinity College Dublin have provided the first crystal clear molecular blueprint of Globomycin - an antibacterial candidate with promise in stemming the onrushing post-antibiotic tide.
Biochemistry
Feb 18, 2016
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526
(PhysOrg.com) -- Some drugs may be more effective the longer they last inside the body. To prevent such drugs from being broken down too rapidly, pharmaceutical manufacturers often attach a fluorine-containing structure called ...
Biochemistry
Jun 24, 2010
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0
Aryl alkyl ethers are important structural motifs found in many biologically active compounds. Therefore, stereoselective etherification is a highly important synthetic operation in the preparation of drug candidates. However, ...
Biochemistry
Sep 15, 2015
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20
Scientists using a technology called cryo-EM (cryo-electron microscopy) have broken through a technological barrier in visualizing proteins with an approach that may have an impact on drug discovery and development. They ...
Biochemistry
May 26, 2016
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191
A quicker and cheaper technique to scan molecular databases developed at the Department of Energy's Oak Ridge National Laboratory could put scientists on the fast track to developing new drug treatments.
Other
Dec 9, 2010
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0
Every organ in the body is capable, to some extent, of repairing itself after an injury. As part of this process, scar tissue forms and then recedes to make room for normal tissue when healing is complete.
Cell & Microbiology
Dec 11, 2019
0
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