CRISPR insight: How to fine-tune Cas protein's grip on DNA

At the heart of every CRISPR reaction, whether naturally occurring in bacteria or harnessed by CRIPSR-Cas gene editing technology, is a strong molecular bond of a Cas protein via a guide RNA to its target site on DNA. It's ...

A new era of mitochondrial genome editing has begun

Researchers from the Center for Genome Engineering within the Institute for Basic Science developed a new gene-editing platform called transcription activator-like effector-linked deaminases, or TALED. TALEDs are base editors ...

Machine learning predicts antibiotic resistance spread

Genes aren't only inherited through birth. Bacteria have the ability to pass genes to each other, or pick them up from their environment, through a process called horizonal gene transfer, which is a major culprit in the spread ...

New approach can add diversity to crop species without breeding GMOs

Breeding better crops through genetic engineering has been possible for decades, but the use of genetically modified plants has been limited by technical challenges and popular controversies. A new approach potentially solves ...

Understanding how genetic motifs conduct 'the music of life'

Our genetic codes control not only which proteins our cells produce, but also—to a great extent—in what quantity. This groundbreaking discovery, applicable to all biological life, was recently made by systems biologists ...

page 2 from 10