Understanding how genetic motifs conduct 'the music of life'

Our genetic codes control not only which proteins our cells produce, but also—to a great extent—in what quantity. This groundbreaking discovery, applicable to all biological life, was recently made by systems biologists ...

Researchers report new technique to image the cell nucleus

Nestled deep in the nucleus of each of your cells is what seems like a magic trick: Six feet of DNA is packaged into a tiny space 50 times smaller than the width of a human hair. Like a long, thin string of genetic spaghetti, ...

Rules of resistance against transgene silencing

Clear rules for engineering transgenes that can be inserted and propagated over multiple generations of nematodes include ways to protect inserted genes from the organism's natural defenses against foreign DNA. Developed ...

The world's first DNA 'tricorder' in your pocket

Cold Spring Harbor Laboratory (CSHL) scientists developed the world's first mobile genome sequence analyzer, a new iPhone app called iGenomics. By pairing an iPhone with a handheld DNA sequencer, users can create a mobile ...

Molecular forces: The surprising stretching behavior of DNA

When large forces act on a heavy beam, for example, in bridge construction, the beam will be slightly deformed. Calculating the relationship between forces, internal stresses and deformations is one of the standard tasks ...

Unlocking PNA's superpowers for self-assembling nanostructures

Researchers at Carnegie Mellon University have developed a method for self-assembling nanostructures with gamma-modified peptide nucleic acid (γPNA), a synthetic mimic of DNA. The process has the potential to impact nanomanufacturing ...

Droplets are key to cells' dynamic activities

A cell is a complex machine whose flexible architecture enables it to take part in life's activities: relaying information, managing waste, responding to stress.

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