Purdue researchers have devised a way to capture the finer details of complex cell processes by using tiny synthetic particles known as dendrimers, a technology that could lead to more targeted treatment for cancer.
Bio & Medicine
Nov 11, 2015
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34
A new slow-motion method of controlling the synthesis of polymers, which takes inspiration from both trees and Celtic Knots, opens up new possibilities in areas including medical devices, drug delivery, elastics and adhesives.
Polymers
May 22, 2013
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0
Head and neck cancer, the sixth most common cancer in the world, has remained one of the more difficult malignancies to treat, and even when treatment is successful, patients suffer severely from the available therapies. ...
Bio & Medicine
Jul 15, 2011
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Hitching a ride into the retina on nanoparticles called dendrimers offers a new way to treat age-related macular degeneration and retinitis pigmentosa. A collaborative research study among investigators at Wayne State University, ...
Bio & Medicine
Dec 13, 2011
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An octopus-like polymer can "walk" along the wall of a narrow channel as it is pushed through by a solvent. Now research in The Journal of Chemical Physics, which is published by the American Institute of Physics, provides ...
Polymers
Aug 3, 2010
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0
Researchers in Japan have found a way to create innovative materials by blending metals with precision control. Their approach, based on a concept called atom hybridization, opens up an unexplored area of chemistry that could ...
Materials Science
Sep 24, 2018
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52
T cells, also known as lymphocytes, have important roles in various immune reactions. However, there are only a few reports on delivery systems into T cells.
Bio & Medicine
Feb 16, 2022
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34
University of Florida chemists have pioneered a method to tease out promising molecular structures for capturing energy, a step that could speed the development of more efficient, cheaper solar cells.
Materials Science
Oct 8, 2009
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Tiny synthetic particles known as dendrimers avoid detection by our immune system and could help develop a new way to deliver drugs into the body without triggering a reaction.
Bio & Medicine
Aug 12, 2021
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219
A research team from the Skoltech Center for Design, Manufacturing and Materials (CDMM) has prepared a comprehensive overview of research on a family of sulfonimide dendrimers that holds promise for optics, photonics, and ...
Polymers
Dec 29, 2020
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10
Dendrimers are repetitively branched molecules. The name comes from the Greek word "δένδρον" (pronounced dendron), which translates to "tree". Synonymous terms for dendrimer include arborols and cascade molecules. However, dendrimer is currently the internationally accepted term. A dendrimer is typically symmetric around the core, and often adopts a spherical three-dimensional morphology. The word dendron is also encountered frequently. A dendron usually contains a single chemically addressable group called the focal point. The difference between dendrons and dendrimers is illustrated in figure one, but the terms are typically encountered interchangeably.
The first dendrimers were made by divergent synthesis approaches by Fritz Vögtle in 1978, R.G. Denkewalter at Allied Corporation in 1981, Donald Tomalia at Dow Chemical in 1983 and in 1985, and by George Newkome in 1985. In 1990 a convergent synthetic approach was introduced by Jean Fréchet. Dendrimer popularity then greatly increased, resulting in more than 5,000 scientific papers and patents by the year 2005.
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