News tagged with dendrimers
Dendrimer
Dendrimers are repetitively branched molecules. The name comes from the Greek word "δένδρον" (pronounced dendron), which translates to "tree". Synonymous terms for dendrimer include arborols and cascade molecules. However, dendrimer is currently the internationally accepted term. A dendrimer is typically symmetric around the core, and often adopts a spherical three-dimensional morphology. The word dendron is also encountered frequently. A dendron usually contains a single chemically addressable group called the focal point. The difference between dendrons and dendrimers is illustrated in figure one, but the terms are typically encountered interchangeably.
The first dendrimers were made by divergent synthesis approaches by Fritz Vögtle in 1978, R.G. Denkewalter at Allied Corporation in 1981, Donald Tomalia at Dow Chemical in 1983 and in 1985, and by George Newkome in 1985. In 1990 a convergent synthetic approach was introduced by Jean Fréchet. Dendrimer popularity then greatly increased, resulting in more than 5,000 scientific papers and patents by the year 2005.
For more information about Dendrimer, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
Nanoparticles help researchers deliver steroids to retina
Hitching a ride into the retina on nanoparticles called dendrimers offers a new way to treat age-related macular degeneration and retinitis pigmentosa. A collaborative research study among investigators at Wayne State University, ...
Nanotechnology / Bio & Medicine
Dec 13, 2011 |
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Polymeric nanoparticles attack head and neck cancer
Head and neck cancer, the sixth most common cancer in the world, has remained one of the more difficult malignancies to treat, and even when treatment is successful, patients suffer severely from the available therapies. ...
Nanotechnology / Bio & Medicine
Jul 15, 2011 |
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Molecules delivering drugs as they walk
An octopus-like polymer can "walk" along the wall of a narrow channel as it is pushed through by a solvent. Now research in The Journal of Chemical Physics, which is published by the American Institute of Physics, provid ...
Aug 03, 2010 |
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Toward better solar cells: Chemists gain control of light-harvesting paths
University of Florida chemists have pioneered a method to tease out promising molecular structures for capturing energy, a step that could speed the development of more efficient, cheaper solar cells.
Oct 08, 2009 |
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Search results for dendrimers
'Green' nanoparticles, that may enhance medication delivery and improve MRI performance
Researchers at Harvard-affiliated McLean Hospital have shown a new category of "green" nanoparticles comprised of a non-toxic, protein-based nanotechnology that can non-invasively cross the blood brain barrier and is capable ...
Nanotechnology / Bio & Medicine
May 02, 2012 |
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Biocompatible quantum dot images tumors in live animals
Quantum dots, small semiconductor nanoparticles that fluoresce brightly with sharply defined colors, have tremendous promise as biomedical imaging agents except for one problemmost are made from potentially hazardous ...
Nanotechnology / Bio & Medicine
Jan 20, 2012 |
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Chemists become molecular sculptors, synthesizing tiny, molecular traps
(PhysOrg.com) -- Using clever but elegant design, University at Buffalo chemists have synthesized tiny, molecular cages that can be used to capture and purify nanomaterials.
Nanotechnology / Nanomaterials
Dec 05, 2011 |
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Molecules on branched-polymer surfaces can capture rare tumor cells in blood
The removal of rare tumor cells circulating in the blood might be possible with the use of biomolecules bound to dendrimers, highly branched synthetic polymers, which could efficiently sift and capture the diseased cells, ...
Nov 17, 2011 |
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Scientists engineer nanoscale vaults to encapsulate 'nanodisks' for drug delivery
(PhysOrg.com) -- There's no question, drugs work in treating disease. But can they work better, and safer?
Nanotechnology / Bio & Medicine
Apr 21, 2011 |
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Mimicking Mother Nature yields promising materials for drug delivery, other applications
Mimicking Mother Nature's genius as a designer is one of the most promising approaches for developing new medicines, sustainable sources of food and energy, and other products that society needs to meet the great challenges ...
Mar 29, 2011 |
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Nanoparticle blocks key molecule involved in spread of breast cancer
Ongoing clinical trials have shown that a peptide known as PHSCN can slow or prevent the spread of metastatic breast cancer in over a third of patients treated with the drug. This drug works by binding to an activated receptor ...
Nanotechnology / Bio & Medicine
Jan 19, 2011 |
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Tangling the microscopic ladder
If a ladder had more than one rung at each step, it would look awkward and would be a bit dangerous to climb. Ladders in the microscopic world were thought to be similar in structure, having only one particle, ...
Dec 17, 2010 |
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Selective estrogen targeting to protect the heart and blood vessels
Diseases of the blood vessels and heart, which are known as cardiovascular diseases, are the most common causes of death in the US. They include heart failure and atherosclerosis (also known as hardening of the arteries), ...
Medicine & Health / Medical research
Jun 23, 2010 |
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Chemists mimic library of bio-membranes for use in nanomedicine, drug delivery
An international collaboration led by chemists and engineers from the University of Pennsylvania has prepared a library of synthetic biomaterials that mimic cellular membranes and that show promise in targeted ...
Nanotechnology / Bio & Medicine
May 20, 2010 |
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List of search results for dendrimers