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Dendrimer

Dendrimers are repetitively branched molecules. The name comes from the Greek word "δένδρον" (pronounced dendron), which translates to "tree". Synonymous terms for dendrimer include arborols and cascade molecules. However, dendrimer is currently the internationally accepted term. A dendrimer is typically symmetric around the core, and often adopts a spherical three-dimensional morphology. The word dendron is also encountered frequently. A dendron usually contains a single chemically addressable group called the focal point. The difference between dendrons and dendrimers is illustrated in figure one, but the terms are typically encountered interchangeably.

The first dendrimers were made by divergent synthesis approaches by Fritz Vögtle in 1978, R.G. Denkewalter at Allied Corporation in 1981, Donald Tomalia at Dow Chemical in 1983 and in 1985, and by George Newkome in 1985. In 1990 a convergent synthetic approach was introduced by Jean Fréchet. Dendrimer popularity then greatly increased, resulting in more than 5,000 scientific papers and patents by the year 2005.

For more information about Dendrimer, read the full article at Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.

Nanoparticles help researchers deliver steroids to retina

Hitching a ride into the retina on nanoparticles called dendrimers offers a new way to treat age-related macular degeneration and retinitis pigmentosa. A collaborative research study among investigators at Wayne State University, ...

Nanotechnology / Bio & Medicine

created Dec 13, 2011 | popularity not rated yet | comments 0

Polymeric nanoparticles attack head and neck cancer

Head and neck cancer, the sixth most common cancer in the world, has remained one of the more difficult malignancies to treat, and even when treatment is successful, patients suffer severely from the available therapies. ...

Nanotechnology / Bio & Medicine

created Jul 15, 2011 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Molecules delivering drugs as they walk

An octopus-like polymer can "walk" along the wall of a narrow channel as it is pushed through by a solvent. Now research in The Journal of Chemical Physics, which is published by the American Institute of Physics, provid ...

Chemistry / Polymers

created Aug 03, 2010 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Toward better solar cells: Chemists gain control of light-harvesting paths

University of Florida chemists have pioneered a method to tease out promising molecular structures for capturing energy, a step that could speed the development of more efficient, cheaper solar cells.

Chemistry / Materials Science

created Oct 08, 2009 | popularity 3 / 5 (2) | comments 0




Search results for dendrimers


'Green' nanoparticles, that may enhance medication delivery and improve MRI performance

Researchers at Harvard-affiliated McLean Hospital have shown a new category of "green" nanoparticles comprised of a non-toxic, protein-based nanotechnology that can non-invasively cross the blood brain barrier and is capable ...

Nanotechnology / Bio & Medicine

created May 02, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Biocompatible quantum dot images tumors in live animals

Quantum dots, small semiconductor nanoparticles that fluoresce brightly with sharply defined colors, have tremendous promise as biomedical imaging agents except for one problem—most are made from potentially hazardous ...

Nanotechnology / Bio & Medicine

created Jan 20, 2012 | popularity 4 / 5 (4) | comments 0 | with audio podcast

Chemists become molecular sculptors, synthesizing tiny, molecular traps

(PhysOrg.com) -- Using clever but elegant design, University at Buffalo chemists have synthesized tiny, molecular cages that can be used to capture and purify nanomaterials.

Nanotechnology / Nanomaterials

created Dec 05, 2011 | popularity 5 / 5 (3) | comments 1 | with audio podcast

Molecules on branched-polymer surfaces can capture rare tumor cells in blood

The removal of rare tumor cells circulating in the blood might be possible with the use of biomolecules bound to dendrimers, highly branched synthetic polymers, which could efficiently sift and capture the diseased cells, ...

Chemistry / Biochemistry

created Nov 17, 2011 | popularity not rated yet | comments 0 | with audio podcast

Scientists engineer nanoscale vaults to encapsulate 'nanodisks' for drug delivery

(PhysOrg.com) -- There's no question, drugs work in treating disease. But can they work better, and safer?

Nanotechnology / Bio & Medicine

created Apr 21, 2011 | popularity not rated yet | comments 0 | with audio podcast

Mimicking Mother Nature yields promising materials for drug delivery, other applications

Mimicking Mother Nature's genius as a designer is one of the most promising approaches for developing new medicines, sustainable sources of food and energy, and other products that society needs to meet the great challenges ...

Chemistry / Materials Science

created Mar 29, 2011 | popularity not rated yet | comments 0

Nanoparticle blocks key molecule involved in spread of breast cancer

Ongoing clinical trials have shown that a peptide known as PHSCN can slow or prevent the spread of metastatic breast cancer in over a third of patients treated with the drug. This drug works by binding to an activated receptor ...

Nanotechnology / Bio & Medicine

created Jan 19, 2011 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Tangling the microscopic ladder

If a ladder had more than one rung at each step, it would look awkward and would be a bit dangerous to climb. Ladders in the microscopic world were thought to be similar in structure, having only one particle, ...

Physics / General Physics

created Dec 17, 2010 | popularity 3 / 5 (1) | comments 0

Selective estrogen targeting to protect the heart and blood vessels

Diseases of the blood vessels and heart, which are known as cardiovascular diseases, are the most common causes of death in the US. They include heart failure and atherosclerosis (also known as hardening of the arteries), ...

Medicine & Health / Medical research

created Jun 23, 2010 | popularity not rated yet | comments 0

Chemists mimic library of bio-membranes for use in nanomedicine, drug delivery

An international collaboration led by chemists and engineers from the University of Pennsylvania has prepared a library of synthetic biomaterials that mimic cellular membranes and that show promise in targeted ...

Nanotechnology / Bio & Medicine

created May 20, 2010 | popularity 5 / 5 (5) | comments 0 | with audio podcast


List of search results for dendrimers