Related topics: genes · genome · cells · dna · cell division

Protein complex SMC shown to ensures the dynamics of holocentromeres

Monocentromeres are typical for the chromosomes of most animals and plants. The centromere is necessary for the transport of the chromosomes and represents the connection point between the chromatids. This is how the classic ...

Chromosome positioning during sperm differentiation described

Chromosomes occupy specific regions of the cell nucleus called chromosome territories. In somatic cells, scientists have observed that there is a correlation between this positioning and genome regulation. In fact, alterations ...

Chromosome separation under focus

During cell division, chromosomes are duplicated and separated so that one copy of each chromosome is inherited by each of the two emerging daughter cells. Correct distribution of chromosomes requires high accuracy and defects ...

Next generation cytogenetics is on its way

Dutch-French research shows that Optical Genome Mapping (OGM) detects abnormalities in chromosomes and DNA very quickly, effectively and accurately. Sometimes even better than all existing techniques together, as they describe ...

Inherited memories of a chromosomal site

Most biological traits are inherited via genes, but there are exceptions to this rule. Two teams from the University of Geneva (UNIGE) have been investigating the location of centromeres—specific sites on chromosomes that ...

Manufacturing the core engine of cell division

It's a cellular process going on since one billion years, yet we are not able to replicate it, nor to fully understand it. Mitosis, the mechanism of cell division that is so important for life, involves more that 100 proteins ...

New method to untangle 3D cancer genome

Northwestern Medicine scientists have invented a new method for resolving rearranged chromosomes and their 3D structures in cancer cells, which can reveal key gene regulators that lead to the development of tumors, published ...

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