Time makes histone H3 modifications drift in mouse liver
Aging is known to involve epigenetic histone modifications, which are associated with transcriptional changes, occurring throughout the entire lifespan of an individual.
Aging is known to involve epigenetic histone modifications, which are associated with transcriptional changes, occurring throughout the entire lifespan of an individual.
Molecular & Computational biology
Jun 30, 2022
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6
A team of researchers at Nagoya University in Japan has created a 3-dimensional computational simulation of the process of genome structure formation in the human cell nucleus. They expect the model to contribute to the understanding ...
Biotechnology
Jun 24, 2022
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77
In almost every human cell, 2 meters of DNA has to fit within a nucleus that is just 8 millionths of a meter wide. Like wool around a spool, the extreme space challenge requires DNA to wrap around structural proteins called ...
Evolution
Jun 9, 2022
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47
Researchers in Japan have discovered that the local DNA motion inside of human cells remains steady throughout interphase, where the cell grows and replicates its DNA for cell division. The study suggests that this steady-state ...
Cell & Microbiology
Jun 3, 2022
1
195
Understanding the molecular mechanisms that specify and maintain the identities of more than 200 cell types of the human body is arguably one of the most fundamental problems in molecular and cellular biology, with critical ...
Molecular & Computational biology
Apr 29, 2022
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143
There are cells in the body known as pluripotent stem cells that are yet to specialize in a particular biological function. These cells maintain the potential to become any of the possible cell types in an organism. Pluripotent ...
Cell & Microbiology
Apr 28, 2022
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12
RIKEN biologists have mapped out key features of the chromosomal landscape that lock in the identity of stem cells that give rise to the mouse placenta. This could aid research into placental function and reproductive medicine.
Cell & Microbiology
Apr 1, 2022
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41
Previously, researchers from Tianjin University designed and created a 254 kb digital data carrying artificial chromosome in yeast. This work "is a key proof-of-concept that demonstrated how artificial chromosomes can be ...
Molecular & Computational biology
Jan 11, 2022
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5
Plant flavonoid accumulation is promoted by various environmental factors, including excess light, UV radiation, drought, and low temperatures. Increased flavonoid content helps plants to maintain normal growth and development ...
Plants & Animals
Dec 21, 2021
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4
Biomedical Engineering Professor Corey Neu and Ph. D. student Benjamin Seelbinder of the University of Colorado at Boulder wanted to answer two fundamental questions. How do cells adapt to their environment and how does a ...
Cell & Microbiology
Dec 2, 2021
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90